Evidence map›Paper›PMID 39462327›Full record

SynthesisBMC cardiovascular disorders2024

Stylet-driven leads compared with lumenless leads for left bundle branch area pacing: a systematic review and meta-analysis.

Xuezhi Chen, Jianzeng Dong

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Outcomes of stylet-driven leads compared to lumenless leads for left bundle branch are pacing: systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  6. Riding the Highs and Lows of the Conduction System Pacing Wave-Our Experience.Journal of cardiovascular development and disease · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xuezhi ChenDepartment of Cardiology, Capital Medical University Affiliated Anzhen Hospital, No.2 of Anzhen Road, Chaoyang District, 100029, Beijing, People's Republic of China.
Jianzeng DongDepartment of Cardiology, Capital Medical University Affiliated Anzhen Hospital, No.2 of Anzhen Road, Chaoyang District, 100029, Beijing, People's Republic of China. jz_dong@126.com.

Funding

Peking University International Hospital Research Funds YN2022ZD05
6 · The paper itself

Abstract

objectiveLeft bundle branch area pacing (LBBAP) is a novel physiological pacing method for treating left ventricular dyssynchrony. LBBAP is often delivered using lumenless leads (LLL). However, recent studies have also reported the use of style-driven leads (SDL). This study is the first systematic review comparing the outcomes of LBBAP with SDL vs. LLL.

methodsThe review and meta-analysis included all available comparative studies published on Embase, PubMed, Web of Science, CENTRAL, and Scopus up to 6th March 2024.

resultsEight observational studies were included in the review. Meta-analysis showed that success rates of LBBAP performed with LLL and SDL were comparable (OR: 1.72 95% CI: 0.94, 3.17 I

conclusionLimited evidence from observational studies with inherent selection bias shows that success rates for LBBAP may not differ between SDL and LLL. While implantation of SDL may be significantly faster, it carries a higher risk of lead dislodgement. Both SDL and LLL are associated with comparable pacing characteristics except for reduced pacing impedance with SDL.

Indexed as

Cardiac Pacing, ArtificialVentricular Function, LeftAction PotentialsAgedBundle of HisEquipment DesignFemaleHeart RateHumansMaleMiddle AgedObservational Studies as TopicPacemaker, ArtificialRecovery of FunctionRisk FactorsTime FactorsConduction-system pacingLBBAPLeadPhysiologic pacing

Identifiers

PMID39462327
PMCPMC11514867

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.