Evidence map›Paper›PMID 39462136›Full record

ArticleScientific reports2024

Ca

Megan M Braun, Brendan K Sheehan, Samantha L Shapiro, Yun Ding, C Dustin Rubinstein, Brent P Lehman, Luigi Puglielli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Gene expression regulation by CaCellular & molecular biology letters · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan M BraunDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Brendan K SheehanDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Samantha L ShapiroDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Yun DingDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA.
C Dustin RubinsteinBiotechnology Center, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Brent P LehmanBiotechnology Center, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Luigi PuglielliDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53705, USA. lp1@medicine.wisc.edu.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Waisman Center Intellectual and Developmental Disabilities Research CenterP50HD105353 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Qiang Chang · 2021 to 2026
$8.5M
Spastic paraplegia, neurodegeneration and autism: possible role for AT- 1/SLC33A1?R01NS094154 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Luigi Puglielli · 2015 to 2026
$4.3M
Creating a region- specific biomolecular atlas of the brain of Alzheimer’s diseaseR01AG078794 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI, Luigi Puglielli · 2022 to 2026
$3.7M
ATase1 and ATase2, proteostasis, and neurological diseasesR01GM148487 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Luigi Puglielli · 2023 to 2026
$1.2M
NCI NIH HHS P30 CA014520NIA NIH HHS AG078794NIA NIH HHS R01 AG078794NICHD NIH HHS P50 HD105353NIGMS NIH HHS GM148487NIGMS NIH HHS R01 GM148487NINDS NIH HHS NS094154NINDS NIH HHS R01 NS094154
6 · The paper itself

Abstract

The acetylation of autophagy protein 9 A (ATG9A) in the lumen of the endoplasmic reticulum (ER) by ATase1 and ATase2 regulates the induction of reticulophagy. Analysis of the ER-specific ATG9A interactome identified calreticulin (CALR), an ER luminal Ca

Indexed as

Autophagy-Related ProteinsCalciumCalreticulinEndoplasmic ReticulumLysineMembrane ProteinsVesicular Transport ProteinsAcetylationAutophagyHEK293 CellsHumansProtein BindingATG9A protein, humanAutophagy-Related ProteinsCalciumCalreticulinCALR protein, humanLysineMembrane ProteinsVesicular Transport ProteinsATG9ACalciumCalreticulinLysine acetylationProteostasisReticulophagy

Identifiers

PMID39462136
PMCPMC11513142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.