Evidence map›Paper›PMID 39462135›Full record

ArticleNature communications2024

A chloroplast localized heavy metal-associated domain containing protein regulates grain calcium accumulation in rice.

Huan Liu, Cun Lu, Xiang-Qian Liu, Chen-Jin Zhuo, Rong-Jian Luo, Qiu-Tang Huang, Zhong Tang, Chun-Qing Zhao, Mary Lou Guerinot, David E Salt and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Huan LiuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.
Cun LuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID 0009-0007-2748-0824
Xiang-Qian LiuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.
Chen-Jin ZhuoState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.
Rong-Jian LuoState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-8588-4022
Qiu-Tang HuangKey Laboratory of Integrated Pest Management on Crops in East China, Ministry of Agriculture, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Zhong TangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.
Chun-Qing ZhaoKey Laboratory of Integrated Pest Management on Crops in East China, Ministry of Agriculture, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Mary Lou GuerinotDepartment of Biological Sciences, Dartmouth College, Hanover, NH, USA.ORCID 0000-0002-4718-4666
David E SaltSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, UK.
Fang-Jie ZhaoState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-0164-169X
Xin-Yuan HuangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China. xinyuan.huang@njau.edu.cn.ORCID 0000-0002-3668-8260

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31772382
6 · The paper itself

Abstract

Calcium (Ca) is an essential mineral nutrient and plays a crucial signaling role in all living organisms. Increasing Ca content in staple foods such as rice is vital for improving Ca nutrition of humans. Here we map a quantitative trait locus that controls Ca concentration in rice grains and identify the causal gene as GCSC1 (Grain Ca and Sr Concentrations 1), which encodes a chloroplast vesicle localized homo-oligomeric protein. GCSC1 exhibits Ca

Indexed as

CalciumChloroplastsOryzaPlant ProteinsAnimalsEdible GrainGene Expression Regulation, PlantMetals, HeavyOocytesPlant LeavesPlants, Genetically ModifiedQuantitative Trait LociXenopus laevisCalciumMetals, HeavyPlant Proteins

Identifiers

PMID39462135
PMCPMC11513116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.