Evidence map›Paper›PMID 39462120›Full record

ArticleNature communications2024

Reentrant DNA shells tune polyphosphate condensate size.

Ravi Chawla, Jenna K A Tom, Tumara Boyd, Nicholas H Tu, Tanxi Bai, Danielle A Grotjahn, Donghyun Park, Ashok A Deniz, Lisa R Racki

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Inorganic Polyphosphate and Human Diseases.Progress in molecular and subcellular biology · 2026
    Review
  5. Article
  6. Protamine Drives Liquid and Solid Condensation of DNA and Glycosaminoglycans.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  7. Article
  8. Polyphosphate: a cellular Swiss army knife.Current opinion in biotechnology · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Cryo-electron tomography of stationary phasemicroPublication biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ravi Chawla *Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0003-1867-9528
Jenna K A Tom *Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0002-1276-1670
Tumara BoydDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0009-0000-3232-7516
Nicholas H TuDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Tanxi BaiDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Danielle A GrotjahnDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0001-5908-7882
Donghyun ParkDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID 0000-0003-2048-6004
Ashok A DenizDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. deniz@scripps.edu.ORCID 0000-0003-2819-4049
Lisa R RackiDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. lracki@scripps.edu.ORCID 0000-0003-2209-7301

Funding

Using phage to interrogate bacterial heterochromatinDP2GM140918 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI RACKI, LISA R · 2020 to 2020
$2.7M
Biophysics of Protein Disorder and Complexity, Single Molecules to MesoscalesR35GM130375 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI DENIZ, ASHOK A · 2019 to 2023
$2.4M
High-speed direct detector for cryo electron microscopyS10OD032467 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI LANDER, GABRIEL C · 2022 to 2022
$600k
American Heart Association (American Heart Association, Inc.) Award #903967NIGMS NIH HHS R35 GM130375NIH HHS S10 OD032467Pew Charitable Trusts Pew Scholars ProgramU.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) DP2-GM-739-140918U.S. Department of Health & Human Services | NIH | NIH Office of the Director (OD) S10OD032467 to Scripps Research for equipment, PI Gabriel Lander
6 · The paper itself

Abstract

The inorganic biopolymer polyphosphate (polyP) occurs in all domains of life and affects myriad cellular processes. A longstanding observation is polyP's frequent proximity to chromatin, and, in many bacteria, its occurrence as magnesium (Mg

Indexed as

DNAMagnesiumPolyphosphatesDNAMagnesiumPolyphosphates

Identifiers

PMID39462120
PMCPMC11513989

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.