Evidence map›Paper›PMID 39462097›Full record

ArticleCommunications biology2024

Endogenous opioid receptor system mediates costly altruism in the human brain.

Jinglu Chen, Vesa Putkinen, Kerttu Seppälä, Jussi Hirvonen, Kalliopi Ioumpa, Valeria Gazzola, Christian Keysers, Lauri Nummenmaa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinglu ChenTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland. jinglu.chen@utu.fi.ORCID 0000-0001-9098-2885
Vesa PutkinenTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.
Kerttu SeppäläTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0003-4068-4059
Jussi HirvonenTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.
Kalliopi IoumpaThe Netherlands Institute for Neuroscience, KNAW research institute, Amsterdam, The Netherlands.
Valeria GazzolaThe Netherlands Institute for Neuroscience, KNAW research institute, Amsterdam, The Netherlands.ORCID 0000-0003-0324-0619
Christian KeysersThe Netherlands Institute for Neuroscience, KNAW research institute, Amsterdam, The Netherlands.ORCID 0000-0002-2845-5467
Lauri NummenmaaTurku PET Centre, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0002-2497-9757

Funding

Academy of Finland (Suomen Akatemia) #332225China Scholarship Council (CSC) 202106040042
6 · The paper itself

Abstract

Functional neuroimaging studies suggest that a large-scale brain network transforms others' pain into its vicarious representation in the observer, potentially modulating helping behavior. However, the neuromolecular basis of individual differences in vicarious pain and helping is poorly understood. We investigated the role of the endogenous μ-opioid receptor (MOR) system in altruistic costly helping. MOR density was measured using [

Indexed as

AltruismBrainMagnetic Resonance ImagingAdultAnalgesics, OpioidFemaleFentanylHumansMalePainReceptors, Opioid, muYoung AdultAnalgesics, OpioidcarfentanilFentanylReceptors, Opioid, mu

Identifiers

PMID39462097
PMCPMC11513155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.