Evidence map›Paper›PMID 39460890›Full record

ArticleAging clinical and experimental research2024

Dynapenic abdominal obesity and activities of daily living disability among older adults residing in low- and middle-income countries.

Lee Smith, Guillermo F López Sánchez, Pinar Soysal, Karel Kostev, Louis Jacob, Nicola Veronese, Mark A Tully, Laurie Butler, Yvonne Barnett, Damiano Pizzol and 2 more

Abstract read
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Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Lee SmithCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Guillermo F López SánchezDivision of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain. gfls@um.es.
Pinar SoysalDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Karel KostevUniversity Clinic of Marburg, Marburg, Germany.
Louis JacobResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain.
Nicola VeroneseGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
Mark A TullySchool of Medicine, Ulster University, Londonderry, UK.
Laurie ButlerCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Yvonne BarnettCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Damiano PizzolItalian Agency for Development Cooperation, Khartoum, Sudan.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. shinji@yuhs.ac.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain.

Funding

Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Harmonizing health outcomes and determinants across longitudinal studies on agingR21AG034263 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH, KOWAL, PAUL R. · 2011 to 2012
$255k
NIA NIH HHS R01 AG034479NIA NIH HHS R21 AG034263
6 · The paper itself

Abstract

backgroundDynapenic abdominal obesity (DAO) may be associated with an increased risk of disability. However, to date, this has not been investigated in low- and middle-income countries (LMICs), while the mediators are largely unknown.

aimsTherefore, we aimed to investigate the association between DAO and activities of daily living (ADL) disability, and to identify potential mediators among older adults from six LMICs.

methodsCross-sectional, nationally representative data from the WHO Study on global AGEing and adult health were analyzed. Data on 20,198 adults aged ≥ 60 years were analyzed [mean (SD) age 69.3 (13.1) years; 54.1% females]. Dynapenia was defined as handgrip strength of < 26 kg for men and < 16 kg for women. Abdominal obesity was defined as waist circumference of > 88 cm for women and > 102 cm for men. DAO was defined as having both dynapenia and abdominal obesity. Disability was defined as severe or extreme difficulty in conducting at least one of six types of ADL. Multivariable logistic regression and mediation analysis were conducted.

resultsCompared to no dynapenia and no abdominal obesity, DAO was significantly associated with 2.08 (95%CI = 1.37-3.17) times higher odds for ADL disability Mediation analysis showed that diabetes (mediated percentage 4.7%), hypertension (7.2%), and angina (7.7%) were significant mediators in the association between DAO and ADL disability.

conclusionsDAO was associated with increased odds for ADL disability among older adults from LMICs. Future longitudinal studies are warranted to assess temporal associations, and whether addressing or preventing DAO can impact on future occurrence of disability.

Indexed as

Activities of Daily LivingDeveloping CountriesObesity, AbdominalPersons with DisabilitiesAgedAged, 80 and overCross-Sectional StudiesFemaleHand StrengthHumansMaleMiddle AgedWaist CircumferenceADL disabilityDynapenic abdominal obesityLow- and middle-income countriesOlder adults

Identifiers

PMID39460890
PMCPMC11512867

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.