Evidence map›Paper›PMID 39460803›Full record

ArticleArchives of dermatological research2024

A marker of systemic inflammation in hidradenitis suppurativa patients without cardiovascular disease: aortic arch calcification.

Uğur Köktürk, Naile Eriş Güdül, İlke Erbay, Pelin Ertop Doğan, Emel Hazinedar, Furkan Kısa, Rafet Koca, Ahmet Avcı

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Article in Archives of dermatological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Uğur KöktürkDepartment of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Esenköy, Kozlu, Zonguldak, 67000, Turkey. drugurkokturk@gmail.com.ORCID http://orcid.org/0000-0003-0459-9295
Naile Eriş GüdülDepartment of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Esenköy, Kozlu, Zonguldak, 67000, Turkey.ORCID http://orcid.org/0000-0003-4102-081X
İlke ErbayDepartment of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Esenköy, Kozlu, Zonguldak, 67000, Turkey.ORCID http://orcid.org/0000-0002-6817-4686
Pelin Ertop DoğanDepartment of Dermatology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.ORCID http://orcid.org/0000-0003-4465-0585
Emel HazinedarDepartment of Dermatology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.ORCID http://orcid.org/0000-0003-3327-0747
Furkan KısaDepartment of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Esenköy, Kozlu, Zonguldak, 67000, Turkey.
Rafet KocaDepartment of Dermatology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.ORCID http://orcid.org/0000-0003-1546-5380
Ahmet AvcıDepartment of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Esenköy, Kozlu, Zonguldak, 67000, Turkey.ORCID http://orcid.org/0000-0003-3434-1711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, we aimed to investigate whether there is a relationship between aortic arch calcification (AAC) and hidradenitis suppurativa (HS) in HS patients without cardiovascular disease.

methodsIn this study, patients over 18 years of age who applied to the dermatology outpatient clinic between January 2023 and February 2024 were followed up with the diagnosis of HS without cardiovascular disease, and a healthy control group matched in terms of age and gender were included retrospectively.

resultsIn total, 130 patients with HS without cardiovascular disease and 130 control patients were included in the study. AAC was significantly higher in the HS group compared to the control group (p = 0.028). In the multivariate analysis, we found that age and HS were independent predictors of AAC (OR: 1.048 (1.009-1.089); p = 0.015, OR: 3.158 (1.181-8.445); p = 0.022, respectively). When we divided the groups as having AAC (grade 1-3) and not having AAC (grade 0), the rate of HS disease was significantly higher in the group with AAC compared to the group without AAC (75.0% vs. 47.5% p = 0.010).

conclusionsAAC is observed more frequently in patients with HS without cardiovascular disease than in healthy individuals. Moreover, HS can be considered as an independent predictor of AAC. AAC may contribute to developing treatment strategies in HS patients without cardiovascular disease.

Indexed as

Aorta, ThoracicHidradenitis SuppurativaAdultAortic DiseasesBiomarkersCardiovascular DiseasesCase-Control StudiesFemaleHumansInflammationMaleMiddle AgedRetrospective StudiesRisk FactorsVascular CalcificationYoung AdultBiomarkersAortic arch calcificationCardiovascular diseaseHidradenitis suppurativaSystemic inflammation

Identifiers

PMID39460803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.