Evidence map›Paper›PMID 39460412›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Piezoelectric Heterojunctions as Bacteria-Killing Bone-Regenerative Implants.

Youzhun Fan, Jinxia Zhai, Zhengao Wang, Zhaoyi Yin, Haoyan Chen, Maofei Ran, Zurong Zhu, Yubin Ma, Chengyun Ning, Peng Yu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. A Piezo-Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Youzhun FanSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Jinxia ZhaiSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Zhengao WangSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Zhaoyi YinFaculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, P. R. China.
Haoyan ChenSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Maofei RanSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Zurong ZhuSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Yubin MaDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, P. R. China.
Chengyun NingSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Peng YuSchool of Materials Science and Engineering, Guang Dong Engineering Technology Research Center of Metallic Materials Surface Functionalization, National Engineering Research Center for Tissue Restoration and Reconstruction, Medical Devices Research and Testing Center, South China University of Technology, Guangzhou, 510641, P. R. China.
Chuanbin MaoDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, P. R. China.ORCID 0000-0002-8142-3659

Funding

China Postdoctoral Science Foundation 2022M711200National Key R&D Program of China 2021YFC2400402National Key R&D Program of China 2021YFC2400405National Natural Science Foundation of China 51932002National Natural Science Foundation of China 52072127National Natural Science Foundation of China 52201297National Natural Science Foundation of China U21A2055National Natural Science Foundation of China U22A20160
6 · The paper itself

Abstract

Heterojunctions are widely used in energy conversion, environmental remediation, and photodetection, but have not been fully explored in regenerative medicine. In particular, piezoelectric heterojunctions have never been examined in tissue regeneration. Here the development of piezoelectric heterojunctions is shown to promote bone regeneration while eradicating pathogenic bacteria through light-cellular force-electric coupling. Specifically, an array of heterojunctions (TiO

Indexed as

Bone RegenerationTitaniumAnimalsAnti-Bacterial AgentsBiocompatible MaterialsHumansNanoparticlesNanowiresOsseointegrationOsteogenesisPhotothermal TherapyProstheses and ImplantsReactive Oxygen SpeciesRegenerative MedicineTungstenAnti-Bacterial AgentsBiocompatible MaterialsReactive Oxygen SpeciesTitaniumtitanium dioxideTungstenantibacterial therapyimplantsinfected bone defectspiezoelectric heterojunctionstissue regeneration

Identifiers

PMID39460412
PMCPMC11707579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.