Evidence map›Paper›PMID 39460357›Full record

ArticleVaccines2024

Pertussis Outbreak During 2023 in Gipuzkoa, North Spain.

José María Marimón, Milagrosa Montes, Nahikari Vizuete, Lorea Alvarez Guerrico, Adrian Hugo Aginagalde, Alba Mir-Cros, Juan José González-López, Diego Vicente

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Antimicrobial resistance inEpidemiology and infection · 2026
    Pooled it
  2. Article
  3. A role for genomics-based studies of Bordetella pertussis adaptation.Current opinion in infectious diseases · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José María MarimónBiogipuzkoa Health Research Institute, Infectious Diseases Area, Microbiology Department, Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Donostia University Hospital, 20014 Donostia-San Sebastian, Spain.ORCID 0000-0002-2787-7094
Milagrosa MontesBiogipuzkoa Health Research Institute, Infectious Diseases Area, Microbiology Department, Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Donostia University Hospital, 20014 Donostia-San Sebastian, Spain.ORCID 0000-0001-6554-4912
Nahikari VizueteSub-Directorate for Public Health and Addictions of Gipuzkoa, Ministry of Health of the Basque Government, 20013 Donostia-San Sebastian, Spain.ORCID 0009-0000-3621-4236
Lorea Alvarez GuerricoSub-Directorate for Public Health and Addictions of Gipuzkoa, Ministry of Health of the Basque Government, 20013 Donostia-San Sebastian, Spain.
Adrian Hugo AginagaldeSub-Directorate for Public Health and Addictions of Gipuzkoa, Ministry of Health of the Basque Government, 20013 Donostia-San Sebastian, Spain.ORCID 0000-0002-5879-2894
Alba Mir-CrosDepartment of Clinical Microbiology, Vall d'Hebron Hospital Universitari, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Juan José González-LópezDepartment of Clinical Microbiology, Vall d'Hebron Hospital Universitari, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.ORCID 0000-0003-2419-5909
Diego VicenteBiogipuzkoa Health Research Institute, Infectious Diseases Area, Microbiology Department, Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Donostia University Hospital, 20014 Donostia-San Sebastian, Spain.ORCID 0000-0003-3553-4312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPertussis has re-emerged in many countries despite the wide use of vaccines for over 60 years. During 2023, we observed an increase in the incidence of pertussis in Gipuzkoa, north of Spain (with a population of 657,140 inhabitants), mainly affecting children between 11 and 15 years of age.

methodsThis study included all confirmed cases diagnosed by PCR in nasopharyngeal swab samples. The genome of seven isolates collected in 2023 was sequenced.

resultsBetween 2018 and 2023, 884 cases of whooping cough were diagnosed. Pertussis incidence (in cases per 100,000 inhabitants) decreased from 36.7 in 2018 to no cases in 2021, increasing again to 56.8 in 2023. In 2023, the age group of 11-15 years old had the highest incidence rate of 409.3. Only 2 of the 56 children < 6 years old required hospitalization, and there were no deaths. The seven isolates collected in 2023 showed the same BPagST-4 (

conclusionsImmunity waning after the last dose of vaccination at 6 years old, together with the lack of circulation of

Indexed as

Bordetella pertussisoutbreakvaccination

Identifiers

PMID39460357
PMCPMC11511359

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.