Evidence map›Paper›PMID 39460337›Full record

ArticleVaccines2024

Intranasal Trans-Sialidase Vaccine Mitigates Acute and Chronic Pathology in a Preclinical Oral Chagas Disease Model.

Maria Florencia Pacini, Camila Bulfoni Balbi, Brenda Dinatale, Cecilia Farré, Paula Cacik, Florencia Belén Gonzalez, Iván Marcipar, Ana Rosa Pérez

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Nasal vaccination againstFrontiers in immunology · 2025
    Article
  5. RNA and protein immunization withFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria Florencia PaciniInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.
Camila Bulfoni BalbiInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.ORCID 0000-0001-8774-5045
Brenda DinataleInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.ORCID 0000-0001-5780-8439
Cecilia FarréInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.ORCID 0000-0003-4966-1152
Paula CacikLaboratorio de Tecnología Inmunológica, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.
Florencia Belén GonzalezInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.
Iván MarciparLaboratorio de Tecnología Inmunológica, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.
Ana Rosa PérezInstituto de Inmunología Clínica y Experimental de Rosario (IDICER-CONICET), Rosario 2000, Argentina.ORCID 0000-0002-1636-7523

Funding

Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) - Argentina PICT-2021-I-A-01235
6 · The paper itself

Abstract

Chagas disease, caused by

Indexed as

c-di-AMPchronic Chagas cardiomyopathynasal vaccineoral Chagas diseasetrans-sialidaseTrypanosoma cruzi

Identifiers

PMID39460337
PMCPMC11511307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.