Evidence map›Paper›PMID 39460329›Full record

ArticleVaccines2024

SARS-CoV-2 Vaccination in Patients with Cancer and COVID-19 in Mexico.

Corazón Barrientos-Flores, Diana Vilar-Compte, Nancy Martínez-Rivera, Rodrigo Villaseñor-Echavarri, Alexandra Martin-Onraet

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Corazón Barrientos-FloresDepartment of Infectious Diseases, Instituto Nacional de Cancerología, Avenida San Fernando 22, Col. Sección 16 Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0002-7449-5961
Diana Vilar-CompteDepartment of Infectious Diseases, Instituto Nacional de Cancerología, Avenida San Fernando 22, Col. Sección 16 Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.
Nancy Martínez-RiveraDepartment of Infectious Diseases, Instituto Nacional de Cancerología, Avenida San Fernando 22, Col. Sección 16 Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.
Rodrigo Villaseñor-EchavarriDepartment of Infectious Diseases, Instituto Nacional de Cancerología, Avenida San Fernando 22, Col. Sección 16 Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0001-5750-884X
Alexandra Martin-OnraetDepartment of Infectious Diseases, Instituto Nacional de Cancerología, Avenida San Fernando 22, Col. Sección 16 Belisario Domínguez, Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0002-8627-404X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesVaccination is the best preventive measure for SARS-CoV-2 infection; however, efficacy is lower in cancer patients. During the pandemic period, Mexico was characterized by the use of seven different COVID-19 vaccine platforms, and oncologic patients were not prioritized for vaccination. We report the outcomes of COVID-19 in cancer patients after the beginning of the national vaccine campaign in Mexico.

methodsAll patients with cancer and COVID-19 diagnosed at Instituto Nacional de Cancerología from 14 February 2021 to 28 February 2022 were included. Primary outcomes were the proportion of individuals who required hospital admission and/or invasive mechanical ventilation, according to the vaccination status; 30-day mortality; the period of infection; and other cancer-related variables.

resultsA total of 691 patients were included; 524 (76%) had solid tumors (STs), and 167 (24%) had hematologic malignancies (HMs). Patients infected in the first two periods, had lower rates of vaccination and higher rates of mortality and hospitalization compared to those infected in the Omicron period. In the multivariate analysis, vaccination status was independently associated with hospitalization in patients with STs (aOR 0.38, 95%CI 0.19-0.75,

conclusionsVaccination significantly reduced hospital admissions in patients with STs. Infections occurring during the Omicron period were associated with improved outcomes in both ST and HM patients. Despite having a lesser impact in immunosuppressed patients, vaccination is an essential strategy, and access to vaccination campaigns in patients with cancer needs to be prioritized.

Indexed as

cancerCOVID-19 vaccineshematologic malignanciessolid tumors

Identifiers

PMID39460329
PMCPMC11512203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.