Evidence map›Paper›PMID 39460259›Full record

ArticleVaccines2024

Post-Transplantation Seroprotection Rates in Liver, Lung, and Heart Transplant Recipients Vaccinated Pre-Transplantation against Hepatitis B Virus and Invasive Pneumococcal Disease.

Lise Bank Hornung, Sebastian Rask Hamm, Annemette Hald, Zitta Barrella Harboe, Lene Fogt Lundbo, Neval Ete Wareham, Line Dam Heftdal, Christina Ekenberg, Stephanie Bjerrum, Jon Gitz Holler and 7 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lise Bank HornungViro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Sebastian Rask HammViro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-2583-3442
Annemette HaldViro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-6906-8159
Zitta Barrella HarboeDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.ORCID 0000-0001-5552-0095
Lene Fogt LundboDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Neval Ete WarehamDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Line Dam HeftdalViro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Christina EkenbergDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-0137-4269
Stephanie BjerrumDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Jon Gitz HollerDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-6101-6821
Inger Hee Mabuza MathiesenDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Paul Suno KrohnDepartment of Surgical Gastroenterology and Transplantation, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Peter Nissen BjerringDepartment of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Finn GustafssonDepartment of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-2144-341X
Michael PerchDepartment of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0001-9740-1246
Allan RasmussenDepartment of Surgical Gastroenterology and Transplantation, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Susanne Dam NielsenViro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-6391-7455

Funding

Rigshospitalet
6 · The paper itself

Abstract

Vaccination before solid organ transplantation is recommended since post-transplantation immunosuppression is known to impair vaccine responses. However, little is known about post-transplantation seroprotection rates in organ transplant recipients vaccinated pre-transplantation. We aimed to investigate the proportion of transplant recipients vaccinated against hepatitis B virus (HBV) and invasive pneumococcal disease (IPD) pre-transplantation at the time of listing for transplantation with post-transplantation seroprotection. We included 136 solid organ transplant (SOT) recipients vaccinated at the time of listing for transplantation. We investigated post-transplantation antibody concentrations against HBV and IPD. Established antibody thresholds were used to define seroprotection. The proportions of SOT recipients with post-transplantation seroprotection were 27.9% (

Indexed as

hepatitis Binvasive pneumococcal diseasesolid organ transplantationvaccination

Identifiers

PMID39460259
PMCPMC11511315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.