Evidence map›Paper›PMID 39459953›Full record

ArticleViruses2024

Assessment of a Structurally Modified Alternanthera Mosaic Plant Virus as a Delivery System for Sarcoma Cells.

Daria Fayzullina, Tatiana Manukhova, Ekaterina Evtushenko, Sergey Tsibulnikov, Kirill Kirgizov, Ilya Ulasov, Nikolai Nikitin, Olga Karpova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daria FayzullinaGroup of Experimental Biotherapy and Diagnostics, Institute for Regenerative Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-0800-3869
Tatiana ManukhovaDepartment of Virology, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Ekaterina EvtushenkoDepartment of Virology, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-0679-6818
Sergey TsibulnikovGroup of Experimental Biotherapy and Diagnostics, Institute for Regenerative Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-7063-205X
Kirill KirgizovResearch Institute of Pediatric Oncology and Hematology, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 115478 Moscow, Russia.
Ilya UlasovGroup of Experimental Biotherapy and Diagnostics, Institute for Regenerative Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-0818-0363
Nikolai NikitinDepartment of Virology, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-9626-2336
Olga KarpovaDepartment of Virology, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-0605-9033

Funding

Russian Science Foundation 24-14-00032
6 · The paper itself

Abstract

The virions of plant viruses and their structurally modified particles (SP) represent valuable platforms for recombinant vaccine epitopes and antitumor agents. The possibility of modifying their surface with biological compounds makes them a tool for developing medical biotechnology applications. Here, we applied a new type of SP derived from virions and virus-like particles (VLP) of Alternanthera mosaic virus (AltMV) and well-studied SP from Tobacco mosaic virus (TMV). We have tested the ability of SP from AltMV (AltMV SP

Indexed as

Tobacco Mosaic VirusVirionCell Line, TumorDrug Delivery SystemsHumansPlant VirusesSarcomaSarcoma, EwingAlternanthera mosaic virusanticancer agentsEwing sarcomaplant virusstructurally modified spherical particlesTobacco mosaic virus

Identifiers

PMID39459953
PMCPMC11512230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.