Evidence map›Paper›PMID 39459916›Full record

ArticleViruses2024

SARS-CoV-2 Antibody Seroprevalence in Gabon: Findings from a Nationwide Household Serosurvey in a Sub-Saharan Africa Country.

Samira Zoa-Assoumou, Paulin Essone-Ndong, Rafiou Adamou, Sandrine Lydie Oyegue-Liabagui, Amandine Mveang Nzoghe, Bayodé Roméo Adegbite, Armel Mintsa Ndong, Herve Mboyis-Kandem, Marien Juliet Verraldy Magossou Mbadinga, Angelique Ndjoyi-Mbiguino and 9 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Samira Zoa-AssoumouDépartement de Bactériologie-Virologie, Université des Sciences de la Santé (USS), Libreville BP 4009, Gabon.ORCID 0000-0002-2714-1781
Paulin Essone-NdongCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP 118, Gabon.
Rafiou AdamouCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP 118, Gabon.
Sandrine Lydie Oyegue-LiabaguiUnité d'Evolution, Epidémiologie et Résistance Parasitaire, Centre Interdisciplinaire de Recherches Médicales de Franceville (CIRMF), Franceville BP 769, Gabon.
Amandine Mveang NzogheUnité de Recherche et Diagnostics Spécialisé, Service Laboratoire, CHU-Mère-Enfant Fondation Jeanne Ebori, Libreville BP 4009, Gabon.
Bayodé Roméo AdegbiteCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP 118, Gabon.
Armel Mintsa NdongLaboratoire Nationale de Santé Publique (LNSP), Libreville BP 4009, Gabon.
Herve Mboyis-KandemDépartement de Bactériologie-Virologie, Université des Sciences de la Santé (USS), Libreville BP 4009, Gabon.
Marien Juliet Verraldy Magossou MbadingaUnité de Recherche et Diagnostics Spécialisé, Service Laboratoire, CHU-Mère-Enfant Fondation Jeanne Ebori, Libreville BP 4009, Gabon.
Angelique Ndjoyi-MbiguinoDépartement de Bactériologie-Virologie, Université des Sciences de la Santé (USS), Libreville BP 4009, Gabon.
Armel Brice Amalet AkaghaOrganisation Mondiale de la Santé, Libreville BP 4009, Gabon.
Krystina Mengue Me Ngou-MilamaOrganisation Mondiale de la Santé, Libreville BP 4009, Gabon.
Magaran Monzon BagayokoOrganisation Mondiale de la Santé, Libreville BP 4009, Gabon.
Inoua AboubacarOrganisation Mondiale de la Santé, Libreville BP 4009, Gabon.
Jean-Bernard Lekana-DoukiUnité d'Evolution, Epidémiologie et Résistance Parasitaire, Centre Interdisciplinaire de Recherches Médicales de Franceville (CIRMF), Franceville BP 769, Gabon.ORCID 0000-0002-9417-1358
Joel Fleury Djoba SiawayaUnité de Recherche et Diagnostics Spécialisé, Service Laboratoire, CHU-Mère-Enfant Fondation Jeanne Ebori, Libreville BP 4009, Gabon.
Ayola Akim AdegnikaCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné BP 118, Gabon.
Edgard-Brice NgoungouDepartment of Epidemiology-Biostatistics and Medical Informatics (DEBIM), Faculty of Medicine, University of Health Sciences, Libreville BP 4009, Gabon.
Covid-Gabonese Group

Funding

WHO Unity StudiesWorld Health Organization 001
6 · The paper itself

Abstract

Seroconversion surveys of anti-SARS-CoV-2 antibodies provide accurate estimates of the prevalence of SARS-CoV-2 infections. This nationwide population-based cross-sectional serosurvey aimed to evaluate the prevalence of SARS-CoV-2 antibodies among residents in Gabon and compare the estimated cumulative number of COVID-19 cases with the officially registered number of laboratory-confirmed cases up to December 2021. Households in each province were randomly selected. Twenty-eight localities, including sixteen urban and twelve rural, were randomly selected for the study. Whole blood samples were collected in dry tubes from all study participants nationwide within 15 days. Serum samples were used to measure SARS-CoV-2-specific ELISA titers. Overall, data from 1672 households were analyzed. Out of the 3659 participants, 3175 were found to be positive for SARS-CoV-2 antibodies, resulting in a crude seroprevalence of 86.77%. Stratification of study participants by age group showed the highest seroprevalences in the 20-29 and 40-49 age groups with 91.78% (95% CI: 89.5-93.6) and 91.42% (95% CI: 88.7-93.5), respectively. Nyanga province had the lowest prevalence (72.8%), and Estuaire and Ogooué-Lolo provinces had the highest prevalence (90 and 92%). Our results suggest a high transmission rate in the Gabonese population 21 months after the first SARS-CoV-2 case in the country. This high seroprevalence estimate could indicate that the population may not have adequately implemented or appropriately adhered to the applied infection control measures.

Indexed as

Antibodies, ViralCOVID-19SARS-CoV-2AdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFamily CharacteristicsFemaleGabonHumansInfantMaleMiddle AgedAntibodies, ViralantibodyCOVID-19Gabonpopulation-based surveySARS-CoV-2seroprevalence

Identifiers

PMID39459916
PMCPMC11512409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.