The Role of Macrophages in Airway Disease Focusing on Porcine Reproductive and Respiratory Syndrome Virus and the Treatment with Antioxidant Nanoparticles.

Abstract readReview

In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kyuhyung ChoiDepartment of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-1929-7708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung macrophage cells play a critical role in various lung diseases, and their state can change depending on the progression of the disease by inducing either an inflammatory or anti-inflammatory state. In this review, the potential therapeutic effects of treatment with antioxidant nanoparticles in air-borne diseases focusing on porcine reproductive and respiratory virus (PRRSV), considering reactive oxygen species (ROS) as one of the factors that regulate M1 and M2 macrophages in the inflammatory and anti-inflammatory states, respectively, was described. In addition, the author examines the status of protein structure research on CD163 (one of the markers of anti-inflammatory M2 macrophages) in human and veterinary lung diseases.

Indexed as

AntioxidantsNanoparticlesPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusReactive Oxygen SpeciesAnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticCD163 AntigenHumansMacrophagesMacrophages, AlveolarReceptors, Cell SurfaceSwineAntigens, CDAntigens, Differentiation, MyelomonocyticAntioxidantsCD163 AntigenReactive Oxygen SpeciesReceptors, Cell Surfacealveolar macrophagesM1/M2nanomaterialsPRRSVrespiratory diseaseROS

Identifiers

PMID39459897

DOI10.3390/v16101563

PMCPMC11512392

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.