Evidence map›Paper›PMID 39459880›Full record

ArticleViruses2024

Identification of a Novel Antiviral Lectin against SARS-CoV-2 Omicron Variant from Shiitake-Mushroom-Derived Vesicle-like Nanoparticles.

Joshua Wiggins, Shazeed-Ul Karim, Baolong Liu, Xingzhi Li, You Zhou, Fengwei Bai, Jiujiu Yu, Shi-Hua Xiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joshua WigginsNebraska Center for Virology, University of Nebraska-Lincoln, Morrison Center 143, 4240 Fair Street, Lincoln, NE 68583, USA.ORCID 0000-0002-8574-5073
Shazeed-Ul KarimDepartment of Cell and Molecular Biology, School of Biological, Environmental, and Earth Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Baolong LiuDepartment of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Xingzhi LiDepartment of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0002-2784-4575
You ZhouSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Fengwei BaiDepartment of Cell and Molecular Biology, School of Biological, Environmental, and Earth Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Jiujiu YuDepartment of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Shi-Hua XiangNebraska Center for Virology, University of Nebraska-Lincoln, Morrison Center 143, 4240 Fair Street, Lincoln, NE 68583, USA.ORCID 0000-0002-5656-5698

Funding

NIH T-32 fellowship grant 5T32NS105594
6 · The paper itself

Abstract

Lectins are a class of carbohydrate-binding proteins that may have antiviral activity by binding to the glycans on the virion surface to interfere with viral entry. We have identified a novel lectin (named Shictin) from Shiitake mushroom (

Indexed as

Antiviral AgentsLectinsNanoparticlesSARS-CoV-2Shiitake MushroomsAnimalsChlorocebus aethiopsCOVID-19COVID-19 Drug TreatmentExosomesHumansVero CellsVirus InternalizationAntiviral AgentsLectinsexosomesextracellular vesicles (EVs)lectinSARS-CoV-2Shictinshiitake mushroomvegetablevesicle-like nanoparticles (VLNs)

Identifiers

PMID39459880
PMCPMC11512411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.