Evidence map›Paper›PMID 39459806›Full record

ArticleMaterials (Basel, Switzerland)2024

Bioactive Self-Polymerizing Resin with Surface Pre-Reacted Glass Ionomer Fillers for Suppressed Enamel Demineralization.

Naoyuki Kaga, Masayuki Kaga, Sho Morita, Futami Nagano-Takebe, Takashi Nezu, Kazuhiko Endo, Takashi Matsuura

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naoyuki KagaSection of Fixed Prosthodontics, Department of Oral Rehabilitation, Fukuoka Dental College, Fukuoka 814-0193, Japan.ORCID 0000-0002-5904-2665
Masayuki KagaDivision of Biomaterials and Bioengineering, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu 061-0293, Japan.
Sho MoritaSection of Fixed Prosthodontics, Department of Oral Rehabilitation, Fukuoka Dental College, Fukuoka 814-0193, Japan.
Futami Nagano-TakebeDivision of Biomaterials and Bioengineering, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu 061-0293, Japan.
Takashi NezuDivision of Biomaterials and Bioengineering, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu 061-0293, Japan.
Kazuhiko EndoDivision of Biomaterials and Bioengineering, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu 061-0293, Japan.
Takashi MatsuuraSection of Fixed Prosthodontics, Department of Oral Rehabilitation, Fukuoka Dental College, Fukuoka 814-0193, Japan.

Funding

Japan Society for the Promotion of Science 23K16056
6 · The paper itself

Abstract

The treatment of damaged enamel surfaces involves modification of the enamel surface with artificial materials or the development of a pseudo-enamel, with research focusing on bioactive and biomimetic materials. In this study, a bioactive auto-polymerizing resin (APR) was developed by adding surface-pre-reacted glass ionomer (S-PRG) fillers of different quantities to APR. Its bioactive effects were evaluated via pH neutralization, ion release, and inhibition of enamel demineralization studies. The pH and fluoride ion release were measured using ion-specific electrodes, revealing that the APR disk with the S-PRG filler immediately neutralized the lactic acid solution (pH 4.0) through ion release. Inductively coupled plasma atomic emission spectrometry revealed that the Sr ion release peaked on the first day, with the other ions following the order F > B > Si > Al > Na, exhibiting a weekly decrease in the same order. Scanning electron microscopy was used to examine the enamel block morphology of the disks after 7 d of incubation, revealing enamel demineralization in disks without the S-PRG filler, whereas no demineralization occurred in disks with the S-PRG filler. APR containing the S-PRG filler demonstrated acid buffering suppressed enamel demineralization and bioactive properties.

Indexed as

acid buffering capacityauto-polymerizing resinbioactivityenamel demineralizationion releaseprovisional restorationS-PRG filler

Identifiers

PMID39459806
PMCPMC11509201

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.