Evidence map›Paper›PMID 39459606›Full record

ReviewLife (Basel, Switzerland)2024

Moderate Sedation or Deep Sedation for ERCP: What Are the Preferences in the Literature?

Giuseppinella Melita, Vincenzo Francesco Tripodi, Socrate Pallio, Endrit Shahini, Alessandro Vitello, Emanuele Sinagra, Antonio Facciorusso, Anna Teresa Mazzeo, Arup Choudhury, Jahnvi Dhar and 2 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07699731 (The Effect of Pre-procedural Anxiety Level on Procedure Tolerability and Quality of ERCP in Consciously Sedated Patients), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07699731 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Pre-procedural Anxiety Level on Procedure Tolerability and Quality of ERCP in Consciously Sedated Patients

TypeobservationalSponsorMandip RaiRan2026 to 2027Enrolled200ConditionsAnxiety, Biliary and Pancreatic Diseases, ERCPArmsNot applicable- observational study
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giuseppinella MelitaHuman Pathology Department, University of Messina, 98124 Messina, Italy.ORCID 0000-0002-4988-333X
Vincenzo Francesco TripodiAnesthesia and Intensive Care, Human Pathology Department, University of Messina, 98124 Messina, Italy.ORCID 0000-0002-1661-6171
Socrate PallioClinical and Experimental Medicine Department, University of Messina, 98124 Messina, Italy.
Endrit ShahiniGastroenterology Unit, National Institute of Gastroenterology, IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.ORCID 0000-0002-4909-0436
Alessandro VitelloGastroenterology and Endoscopy Unit, S. Elia-Raimondi Hospital, 93100 Caltanissetta, Italy.
Emanuele SinagraGastroenterology and Endoscopy Unit, Fondazione Istituto San Raffaele Giglio, 90015 Cefalù, Italy.
Antonio FacciorussoGastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.ORCID 0000-0002-2107-2156
Anna Teresa MazzeoAnesthesia and Intensive Care, Human Pathology Department, University of Messina, 98124 Messina, Italy.
Arup ChoudhuryGastroenterology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Jahnvi DharGastroenterology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-6929-4276
Jayanta SamantaGastroenterology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-9277-5086
Marcello Fabio MaidaDepartment of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.ORCID 0000-0002-4992-9289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most essential procedures for individuals with biliopancreatic disorders is endoscopic retrograde cholangiopancreatography (ERCP). It is based on the combination of endoscopy and radiology to study the biliopancreatic ducts and apply therapeutic solutions. ERCP is currently used to treat choledocholithiasis with or without cholangitis, as well as pancreatic duct stones, benign bile, and pancreatic leaks. On the other hand, ERCP is an unpleasant procedure that must be conducted under anesthetic (moderate sedation, deep sedation, or general anesthesia). With procedures becoming more challenging, the role of anesthesia in ERCP has become even more relevant, and the use of general anesthesia has become better defined. In the last decades, many drugs have been used and some new drugs, like dexmedetomidine, have been recently introduced for sedation or anesthesia during ERCP. Moreover, the scientific community is still divided on the level of sedation to be applied, as well as on appropriate airway management. We therefore performed a narrative review of the literature to assess currently available anesthetic medications for elective ERCP and evidence supporting their effectiveness.

Indexed as

anesthesiadeep sedationendoscopic retrograde cholangiopancreatographyliterature reviewmoderate sedation

Identifiers

PMID39459606
PMCPMC11509070

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.