ArticleLife (Basel, Switzerland)2024
Lymphocyte to White Blood Cell Count Ratio an Independent Risk Factor for Heart Failure.
Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association of the C-reactive protein-albumin-lymphocyte index with heart failure prevalence and mortality risk in older adults with hypertension: A cohort study.The Journal of international medical research · 2026Article
- Bridging Gaps in Heart Failure Science: Toward a More Integrated Future.Life (Basel, Switzerland) · 2025Article
- Interpretable Machine Learning Approach for Predicting 30-Day Mortality of Critical Ill Patients with Pulmonary Embolism and Heart Failure: A Retrospective Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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Authors and funding
4 authors.
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Abstract
objectiveHeart failure affects 1-2% of the population in developed countries. Hemogram biomarkers are cheap, rapid, readily accessible and are known to have prognostic benefit in cardiovascular, infectious and oncologic diseases.
methodsThe aim of the current study is to evaluate lymphocyte-to-white-blood-cell ratio (LWR) as a prognostic predictor in patients with heart failure. Patients with heart failure were recruited between January 2000 and July 2001. Exclusion criteria included metastatic malignancy, exposure to chemotherapy, radiotherapy or medications known to affect complete blood count.
results338 patients were enrolled, 33 were excluded. Mean age was 70.1 ± 10.8, 225 patients were male (73%) and 80 were female (27%). All patients were divided into three groups according to LWR. Group 1 < 0.2, group 2-0.2 < LWR < 0.35 and group 3 > 0.35. Patients with LWR ratio < 0.2 had the poorest survival while patients in the highest LWR (ratio > 0.35) had the best long-term survival.
conclusionsPatients with congestive heart failure and LWR < 0.2 showed significant increased mortality. LWR was shown as independent prognostic predictor for HF patients compared to other main outcome parameters, including CRP, NYHA, EF and LDL.
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