Evidence map›Paper›PMID 39459516›Full record

ArticleLife (Basel, Switzerland)2024

Association of Loneliness with Functional and Cognitive Status in Minor and Major Neurocognitive Disorders.

Maria Claudia Moretti, Iris Bonfitto, Luciano Nieddu, Ivana Leccisotti, Savino Dimalta, Giovanni Moniello, Madia Lozupone, Antonello Bellomo, Francesco Panza, Carlo Avolio and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Claudia MorettiDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Iris BonfittoDepartment of Mental Health, Azienda Sanitaria Locale Foggia, 71121 Foggia, Italy.
Luciano NiedduDepartment of International Humanist and Social Studies, University of International Studies of Rome, 00147 Rome, Italy.ORCID 0000-0001-5174-3347
Ivana LeccisottiDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0009-0000-0359-4471
Savino DimaltaDepartment of Mental Health, Azienda Sanitaria Locale Foggia, 71121 Foggia, Italy.
Giovanni MonielloDepartment of Medical Area, UOSD "Lungodegenza" P.O. di San Felice a Cancello, 81100 Caserta, Italy.
Madia LozuponeDepartment of Translational Biomedicine and Neuroscience "DiBraiN", University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-1674-9724
Antonello BellomoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Francesco PanzaDepartment of Interdisciplinary Medicine, "Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-7220-0656
Carlo AvolioDepartment of Medical and Surgical Specialities, University of Foggia, 71122 Foggia, Italy.
Mario AltamuraDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurocognitive disorders (NCDs) have a variable decline in cognitive function, while loneliness was associated with cognitive impairment and increased dementia risk. In the present study, we examined the associations of loneliness with functional and cognitive status in patients with minor (mild cognitive impairment) and major NCDs (dementia).

methodsWe diagnosed mild NCD (

resultsIn a multivariate regression model, the effect of loneliness on cognitive functions was negative in major (β = -1.05,

conclusionsWe confirmed the relationships between loneliness and cognitive and functional status in major NCD, observing a novel trend in minor NCD.

Indexed as

ADLAlzheimer’s diseasedementiadepressionIADLlonelinessmild cognitive impairmentMMSEmultimorbidity

Identifiers

PMID39459516
PMCPMC11508600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.