Evidence map›Paper›PMID 39459045›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl-Pyridazine Moiety for the Potential Treatment of Alzheimer's Disease.

Mohamed Elsawalhy, Adel A-H Abdel-Rahman, Ebtesam A Basiony, Salma A Ellithy, Allam A Hassan, Eman S Abou-Amra, Abdelhamid Ismail, Abdulrahman A Almehizia, Mohamed A Al-Omar, Ahmed M Naglah and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamed ElsawalhyDepartment of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.ORCID 0009-0007-8741-6146
Adel A-H Abdel-RahmanDepartment of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
Ebtesam A BasionyDepartment of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
Salma A EllithyDepartment of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.ORCID 0009-0001-5697-159X
Allam A HassanDepartment of Chemistry, Faculty of Science, Suez University, Suez 43221, Egypt.
Eman S Abou-AmraDepartment of Chemistry, Organic Chemistry, Faculty of Science (Girls), Al-Azhar University, Cairo 11754, Egypt.ORCID 0000-0002-6267-5834
Abdelhamid IsmailDepartment of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
Abdulrahman A AlmehiziaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8711-3873
Mohamed A Al-OmarDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-9866-343X
Ahmed M NaglahDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4377-5239
Nasser A HassanSynthetic Unit, Department of Photochemistry, Chemical Industries Research Institute, National Research Centre, Cairo 12622, Egypt.ORCID 0000-0003-1809-9232

Funding

King Saud University, Riyadh, Saudi Arabia RSPD2024R852
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetylcholinesteraseAlzheimer’s diseasebutyrylcholinesteraseclick chemistrypyridazinespectroscopic techniques

Identifiers

PMID39459045
PMCPMC11510214

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.