Evidence map›Paper›PMID 39458903›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Roles of Prostaglandins and Hydrogen Sulfide in an Outflow Model of the Porcine Ocular Anterior Segment Ex Vivo.

Jenaye Robinson, Leah Bush, Anthonia Okolie, Fatima Muili, Sunny Ohia, Catherine Opere, Ya Fatou Njie Mbye

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jenaye RobinsonDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Leah BushDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.ORCID 0000-0003-3882-3793
Anthonia OkolieDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Fatima MuiliDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Sunny OhiaDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.
Catherine OpereDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, Omaha, NE 68178, USA.
Ya Fatou Njie MbyeDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.ORCID 0000-0002-1036-7266

Funding

MECHANISM OF IOP-LOWERING EFFECTS OF HYDROGEN SULFIDER15EY032274 · NEI · TEXAS SOUTHERN UNIVERSITY · PI MBYE, YA FATOU NJIE · 2021 to 2021
$459k
HYDROGEN SULFIDE-RELEASING COMPOUNDS AND IOP REGULATIONR15EY022215 · NEI · TEXAS SOUTHERN UNIVERSITY · PI MBYE, YA FATOU NJIE · 2012 to 2012
$419k
National Instittute of Health, National Eye Institute 1RI5EY022215-01National Institue of Health, National Eye Institute 1R15EY032274-01NEI NIH HHS R15 EY022215NEI NIH HHS R15 EY032274
6 · The paper itself

Abstract

backgroundHydrogen sulfide (H MATERIAL AND

methodsPorcine ocular anterior segment explants were perfused with Dulbecco's Modified Eagle's Medium maintained at 37 °C and gassed with 5% CO

resultsElevating perfusion pressure from 7.35 to 15 mm Hg significantly (

conclusionsWe conclude that the elevated perfusion pressure-induced increase in H

Indexed as

aqueous humor outflowhydrogen sulfideperfusion pressureprostaglandinstrabecular meshwork

Identifiers

PMID39458903
PMCPMC11510490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.