Evidence map›Paper›PMID 39458615›Full record

ArticlePharmaceutics2024

Targeting Hypoxia-Inducible Factor-1α in Pancreatic Cancer: siRNA Delivery Using Hyaluronic Acid-Displaying Nanoparticles.

Alice Spadea, Annalisa Tirella, Julio Manuel Rios de la Rosa, Enrique Lallana, Manal Mehibel, Brian Telfer, Nicola Tirelli, Margaret Jayne Lawrence, Kaye J Williams, Ian J Stratford and 1 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alice SpadeaNorthWest Centre for Advanced Drug Delivery (NoWCADD), School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0002-8857-330X
Annalisa TirellaDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0002-3743-3593
Julio Manuel Rios de la RosaNorthWest Centre for Advanced Drug Delivery (NoWCADD), School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0001-9363-1458
Enrique LallanaNorthWest Centre for Advanced Drug Delivery (NoWCADD), School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Manal MehibelDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Brian TelferDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0003-1857-5120
Nicola TirelliDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0002-4879-3949
Margaret Jayne LawrenceNorthWest Centre for Advanced Drug Delivery (NoWCADD), School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0003-4738-4841
Kaye J WilliamsDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Ian J StratfordDivision of Pharmacy and Optometry, School of Health Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Marianne AshfordAdvanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield M13 9PT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancerCD44hyaluronic acidpolymeric nanoparticlessiRNA delivery

Identifiers

PMID39458615
PMCPMC11510765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.