Evidence map›Paper›PMID 39458549›Full record

Trial reportNutrients2024

A One-Week Elderberry Juice Intervention Augments the Fecal Microbiota and Suggests Improvement in Glucose Tolerance and Fat Oxidation in a Randomized Controlled Trial.

Christy Teets, Nancy Ghanem, Guoying Ma, Jagrani Minj, Penelope Perkins-Veazie, Sarah A Johnson, Andrea J Etter, Franck G Carbonero, Patrick M Solverson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christy TeetsDepartment of Nutrition and Exercise Physiology, Elson S Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.
Nancy GhanemDepartment of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-3955-8645
Guoying MaPlants for Human Health Institute, Department of Horticultural Science, North Carolina State University, Kannapolis, NC 28081, USA.
Jagrani MinjDepartment of Nutrition and Exercise Physiology, Elson S Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.
Penelope Perkins-VeaziePlants for Human Health Institute, Department of Horticultural Science, North Carolina State University, Kannapolis, NC 28081, USA.ORCID 0000-0002-5885-0492
Sarah A JohnsonDepartment of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-3423-6911
Andrea J EtterDepartment of Nutrition and Food Science, University of Vermont, Burlington, VT 05405, USA.ORCID 0000-0002-0204-0239
Franck G CarboneroDepartment of Nutrition and Exercise Physiology, Elson S Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.
Patrick M SolversonDepartment of Nutrition and Exercise Physiology, Elson S Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.ORCID 0000-0003-0858-9844

Funding

National Institute of Food and Agriculture 2020-67018-30851
6 · The paper itself

Abstract

Obesity is a costly and ongoing health complication in the United States and globally. Bioactive-rich foods, especially those providing polyphenols, represent an emerging and attractive strategy to address this issue. Berry-derived anthocyanins and their metabolites are of particular interest for their bioactive effects, including weight maintenance and protection from metabolic aberrations. Earlier findings from small clinical trials suggest modulation of substrate oxidation and glucose tolerance with mediation of prospective benefits attributable to the gut microbiota, but mixed results suggest appropriate anthocyanin dosing poses a challenge. The objective of this randomized, placebo-controlled study was to determine if anthocyanin-dense elderberry juice (EBJ) reproduces glucoregulatory and substrate oxidation effects observed with other berries and if this is mediated by the gut microbiota. Overweight or obese adults (BMI > 25 kg/m

Indexed as

FecesFruit and Vegetable JuicesGastrointestinal MicrobiomeSambucusAdultAnthocyaninsBlood GlucoseCross-Over StudiesDouble-Blind MethodFemaleHumansMaleMiddle AgedObesityOverweightOxidation-ReductionAnthocyaninsBlood Glucoseberry anthocyaninsfecal microbiomefunctional foodsinsulin and glucose homeostasismeal tolerance testobesitysubstrate oxidation

Identifiers

PMID39458549
PMCPMC11510622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.