Evidence map›Paper›PMID 39458513›Full record

ReviewNutrients2024

Unveiling the Power of Flax Lignans: From Plant Biosynthesis to Human Health Benefits.

Zhan Gao, Qinglei Cao, Zhongyuan Deng

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Flax Lignans: From Biosynthetic Regulation to Biological Activities.International journal of molecular sciences · 2026
    Review
  3. Genome Editing Approaches in Flax (International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. T2TJournal of fungi (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhan GaoSchool of Physical Education and Training, Capital University of Physical Education and Sports, Beijing 100191, China.
Qinglei CaoDepartment of Physical Education, University of Science and Technology Beijing, Beijing 100083, China.
Zhongyuan DengDepartment of Physical Education, University of Science and Technology Beijing, Beijing 100083, China.

Funding

Beijing Natural Science Foundation in China No. 7224356Provincial Industry-University-Research Cooperation Projects No. 2214003
6 · The paper itself

Abstract

backgroundFlax (

resultsAfter ingestion, it is converted by human intestinal flora into enterodiol and enterolactone, which both have physiological roles. Here, the basic structures, contents, synthesis, regulatory, and metabolic pathways, as well as extraction and isolation methods, of flax lignans were reviewed. Additionally, the physiological activity-related mechanisms and their impacts on human health, from the biosynthesis of lignans in plants to the physiological activity effects observed in animal metabolites, were examined.

conclusionsThe review elucidates that lignans, as phenolic compounds, not only function as active substances in plants but also offer significant nutritional values and health benefits when flax is consumed.

Indexed as

FlaxLignans4-ButyrolactoneAnimalsButylene GlycolsGastrointestinal MicrobiomeHumansNutritive Value2,3-bis(3'-hydroxybenzyl)butane-1,4-diol2,3-bis(3'-hydroxybenzyl)butyrolactone4-ButyrolactoneButylene GlycolsLignanssecoisolariciresinolenterodiolenterolactonelignan metabolismlignan synthesissecoisolariciresinol

Identifiers

PMID39458513
PMCPMC11510306

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.