Evidence map›Paper›PMID 39458508›Full record

ArticleNutrients2024

Macronutrients in Human Milk and Early Childhood Growth-Is Protein the Main Driver?

Jie Ma, Debra J Palmer, Ching Tat Lai, Susan L Prescott, Nina D'Vaz, Philip Vlaskovsky, Lisa F Stinson, Zoya Gridneva, Donna T Geddes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie MaSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0002-4042-3716
Debra J PalmerABREAST Network, Perth, WA 6000, Australia.ORCID 0000-0003-2498-8343
Ching Tat LaiSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0002-9025-4922
Susan L PrescottThe Kids Research Institute Australia, The University of Western Australia, Nedlands, WA 6009, Australia.ORCID 0000-0003-4845-8590
Nina D'VazThe Kids Research Institute Australia, The University of Western Australia, Nedlands, WA 6009, Australia.
Philip VlaskovskySchool of Mathematics and Statistics, The University of Western Australia, Crawley, WA 6009, Australia.
Lisa F StinsonSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0003-2799-2727
Zoya GridnevaSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0001-6841-2958
Donna T GeddesSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.

Funding

Ad Hoc Postgraduate Scholarship from Medela AG NAan additional Scholarships for International Research Fees from The University of Western Australia NAMedela AG (Switzerland) Unrestricted research grantNational Health and Medical Research Council of Australia NHMRC GNT353555The Kids Research Institute Australia Ascend Fellowship NA
6 · The paper itself

Abstract

backgroundInfant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage in infant growth is unclear, protein intake is important for early infancy growth. MATERIALS AND

methodsThis study of exclusively breastfeeding mothers with allergies (

resultsHigher human milk protein:energy ratio was associated with higher weight-for-age z-score at 2.5 years compared to 3 months and higher body mass index-for-age z-score change (6 months to 1 year compared to 3-6 months). Maternal atopy and birth season (summer) were negatively associated with human milk lactose concentration. Passive smoke exposure was associated with reduced energy and fat concentrations and increased lactose:energy ratio.

conclusionsOur results indicate that intake of human milk macronutrients may impact early childhood growth.

Indexed as

Breast FeedingChild DevelopmentMilk, HumanNutrientsAdultBody Mass IndexChild, PreschoolDietary ProteinsEnergy IntakeFemaleHumansHypersensitivityInfantInfant, NewbornInfant Nutritional Physiological PhenomenaLactoseDietary ProteinsLactoseMilk ProteinsNutrientsatopybreastfeedingfathuman milk macronutrientsinfant anthropometricsinfant growthinfant intakelactationlactoseprotein leverage

Identifiers

PMID39458508
PMCPMC11510703

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.