Observational studyNutrients2024
Oral Frailty as a Risk Factor for Malnutrition and Sarcopenia in Patients on Hemodialysis: A Prospective Cohort Study.
Observational study in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The prevalence and associated factors of oral frailty in older Chinese patients with chronic conditions: a systematic review and meta-analysis.BMC geriatrics · 2026Pooled it
- Risk prediction models for oral frailty in older adults: a scoping review.Frontiers in medicine · 2026Pooled it
- Pooled it
- Systematic review and meta-analysis of oral frailty prevalence among older hospitalized patients.Frontiers in public health · 2025Pooled it
- Influencing factors of oral frailty in Chinese maintenance hemodialysis patients: a Bayesian network analysis.Renal failure · 2026Article
- Cultural Adaptation and Validation of the Oral Frailty Index-8 for Turkish Older Adults.Gerodontology · 2026Article
- Influencing factors of oral frailty in elderly patients with head and neck cancer: a multicenter, cross-sectional study.BMC oral health · 2026Observational
- Reliability and Validity of Oral Frailty Index-8: Findings Among Community-Dwelling Adults in Singapore.Journal of oral rehabilitation · 2026Article
- Associations of comprehensive oral health with body composition, physical performance, and sarcopenia among middle-aged and older adults in rural western China: potential mediating pathways.BMC oral health · 2026Article
- Oral frailty in older adults: a scoping review of risk factors, adverse outcomes, and interventions.BMC geriatrics · 2026Article
- Chewing ability and its associated factors in maintenance hemodialysis patients: a cross-sectional study.BMC oral health · 2025Article
- Effect of intradialytic dietary support on nutritional status, muscle strength, and clinical markers in patients on hemodialysis: a cross-sectional study.BMC nephrology · 2025Article
- Association of Oral Frailty with Physical Frailty and Malnutrition in Patients on Peritoneal Dialysis.Nutrients · 2025Article
- Association between the geriatric nutritional risk index and postoperative delirium in gastric surgery patients: an analysis of the MIMIC-IV database.BMC anesthesiology · 2024Article
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7 authors.
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Abstract
backgroundOral frailty is a concept that encompasses various aspects of impaired oral function in elderly people, leading to reduced food intake and less dietary diversity, which can result in sarcopenia and physical frailty. However, there have been no studies on the relationship between oral frailty and malnutrition, sarcopenia, and physical frailty in patients on hemodialysis (HD).
methodsThis prospective observational cohort study assessed the oral status of patients on HD. The patients were divided into an oral frailty group and non-oral frailty group using the Oral Frailty Index-8. Malnutrition was assessed using the Geriatric Nutritional Risk Index (GNRI), the Nutritional Risk Index for Japanese Hemodialysis Patients (NRI-JH), and the Short-Form Mini-Nutritional Assessment (MNA-SF). Sarcopenia was assessed using the Asian Working Group for Sarcopenia 2019's criteria. Physical frailty was assessed using the Japanese version of the Cardiovascular Health Study criteria. One year later, the changes in nutritional status, sarcopenia, and physical frailty risk categories were compared between the oral frailty and non-oral frailty groups.
resultsThe study enrolled 201 patients (non-oral frailty group, 123; oral frailty group, 78). After 1 year, the oral frailty group had a significantly higher proportion of patients with worsening nutrition status (GNRI,
conclusionsOral frailty predicts future malnutrition and the progression of sarcopenia in HD patients. In particular, our results strongly suggested that oral frailty was a strong determinant of worsening malnutrition and sarcopenia in HD patients aged ≥65 years.
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