Evidence map›Paper›PMID 39458125›Full record

ReviewJournal of clinical medicine2024

Head and Neck Cancer (HNC) Prehabilitation: Advantages and Limitations.

Sara Demurtas, Hellas Cena, Marco Benazzo, Paola Gabanelli, Simone Porcelli, Lorenzo Preda, Chandra Bortolotto, Giulia Bertino, Simone Mauramati, Maria Vittoria Veneroni and 5 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of exercise on head and neck cancer surgery: a systematic review of randomized controlled trials.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sara DemurtasInternal Medicine and Therapeutics Department, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1559-3887
Hellas CenaLaboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5752-6199
Marco BenazzoDepartment of Otorhinolaryngology, University of Pavia, 27100 Pavia, Italy.
Paola GabanelliUnit of Psychology, Maugeri Clinical Research Institutes IRCCS, 27100 Pavia, Italy.
Simone PorcelliDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
Lorenzo PredaDiagnostic Imaging and Radiotherapy Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5479-2766
Chandra BortolottoDiagnostic Imaging and Radiotherapy Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-9193-9309
Giulia BertinoDepartment of Otolaryngology-Head and Neck Surgery, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0003-2840-5184
Simone MauramatiDepartment of Otolaryngology-Head and Neck Surgery, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Maria Vittoria VeneroniDepartment of Otolaryngology-Head and Neck Surgery, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Ester OrlandiDepartment of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-6495-8574
Anna Maria CamardaRadiation Oncology Unit, CNAO National Center for Oncological Hadrontherapy, 27100 Pavia, Italy.
Nagaia MadiniLaboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.
Chiara Annamaria RasoInternal Medicine and Therapeutics Department, University of Pavia, 27100 Pavia, Italy.
Laura Deborah LocatiInternal Medicine and Therapeutics Department, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3315-2580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer prehabilitation is the process between the time of cancer diagnosis and the beginning of the active acute treatment; prehabilitation consists of various need-based interventions, e.g., physical activity, a nutritional program, and psychological support. It can be delivered as unimodal or multimodal interventions. Physical activity, including resistant exercise and aerobic activities, has to be tailored according to the patient's characteristics; nutritional support is aimed at preventing malnutrition and sarcopenia; while psychological intervention intercepts the patient's distress and supports specific intervention to address it. In addition, multimodal prehabilitation could have a potential impact on the immune system, globally reducing the inflammatory processes and, as a consequence, influencing cancer progression. However, many challenges are still to be addressed, foremost among them the feasibility of prehabilitation programs, the lack of adequate facilities for these programs' implementation, and the fact that not all prehabilitation interventions are reimbursed by the national health system.

Indexed as

head and neck cancernutritional interventionphysical exerciseprehabilitationpsychological support

Identifiers

PMID39458125
PMCPMC11509296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.