Evidence map›Paper›PMID 39457958›Full record

ArticleAnimals : an open access journal from MDPI2024

Clinical Pathology Evaluation in Pet Rabbits Vaccinated Against Rabbit Hemorrhagic Disease Virus 2 (RHDV2).

Chris Griffin, Salina Locke, Fabiano Montiani-Ferreira, Andressa Lopes Grego, Jeny Soto, Carolyn Cray

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chris GriffinGriffin Avian & Exotic Veterinary Hospital, Kannapolis, NC 28083, USA.
Salina LockeAvian and Exotic Animal Care, Raleigh, NC 27617, USA.ORCID 0000-0001-5289-6951
Fabiano Montiani-FerreiraDepartamento de Medicina Veterinária, Universidade Federal do Paraná, Curitiba 80035-050, PR, Brazil.ORCID 0000-0002-3933-8864
Andressa Lopes GregoDepartamento de Medicina Veterinária, Universidade Federal do Paraná, Curitiba 80035-050, PR, Brazil.
Jeny SotoDivision of Comparative Pathology, Department of Pathology & Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Carolyn CrayDivision of Comparative Pathology, Department of Pathology & Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-7180-153X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recombinant vaccine for rabbit hemorrhagic disease virus 2, a highly pathogenic virus, was granted emergency use authorization in the United States after the detection and spread of the virus starting in 2018. The goal of the current study was to assess pet rabbits (n = 29) through physical examination and routine clinical pathology testing using repeated assessments post-vaccination. In addition, seroconversion was also monitored after the initial vaccination and booster vaccination. Neither owners nor clinicians detected any physical abnormalities in relationship to the vaccine protocol. Hematological and clinical biochemistry testing showed some changes although median values were within species specific reference intervals. A significant increase in antibody levels was observed at day 21 (post-initial vaccination) and day 49 (post-booster vaccination) versus that present at baseline (

Indexed as

antibodybiochemistryELISAhematologylagomorphRHDV2

Identifiers

PMID39457958
PMCPMC11504023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.