Evidence map›Paper›PMID 39457677›Full record

ArticleBiomedicines2024

Bedside Neuromodulation of Persistent Pain and Allodynia with Caloric Vestibular Stimulation.

Trung T Ngo, Wendy N Barsdell, Phillip C F Law, Carolyn A Arnold, Michael J Chou, Andrew K Nunn, Douglas J Brown, Paul B Fitzgerald, Stephen J Gibson, Steven M Miller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Trung T NgoRECOVER Injury Research Centre, The University of Queensland and Surgical, Treatment & Rehabilitation Service (STARS), Herston, Brisbane, QLD 4029, Australia.ORCID 0000-0002-1909-134X
Wendy N BarsdellAdelaide Neuropsychology, Adelaide, SA 5000, Australia.
Phillip C F LawMonash Biomedicine Discovery Institute, Department of Physiology, Monash University, Melbourne, VIC 3800, Australia.
Carolyn A ArnoldCaulfield Pain Management & Research Centre, Caulfield Hospital, The Alfred Health, Melbourne, VIC 3162, Australia.
Michael J ChouAmputee Clinic, Caulfield Hospital, Melbourne, VIC 3162, Australia.
Andrew K NunnAmputee Clinic, Caulfield Hospital, Melbourne, VIC 3162, Australia.ORCID 0000-0002-0222-9410
Douglas J BrownSpinal Research Institute, Austin Health, Melbourne, VIC 3084, Australia.
Paul B FitzgeraldSchool of Medicine and Psychology, Australian National University, Acton, ACT 2600, Australia.ORCID 0000-0003-4217-8096
Stephen J GibsonCaulfield Pain Management & Research Centre, Caulfield Hospital, The Alfred Health, Melbourne, VIC 3162, Australia.
Steven M MillerMonash Biomedicine Discovery Institute, Department of Physiology, Monash University, Melbourne, VIC 3800, Australia.

Funding

National Health and Medical Research Council 1193596National Health and Medical Research Council 490976Victorian Neurotrauma Initiative N/A
6 · The paper itself

Abstract

backgroundCaloric vestibular stimulation (CVS) is a well-established neurological diagnostic technique that also induces many phenomenological modulations, including reductions in phantom limb pain (PLP), spinal cord injury pain (SCIP), and central post-stroke pain.

objectiveWe aimed to assess in a variety of persistent pain (PP) conditions (i) short-term pain modulation by CVS relative to a forehead ice pack cold-arousal control procedure and (ii) the duration and repeatability of CVS modulations. The tolerability of CVS was also assessed and has been reported separately.

methodsWe conducted a convenience-based non-randomised single-blinded placebo-controlled study. Thirty-eight PP patients were assessed (PLP,

resultsAcross all groups, NRS-PI for pain was significantly lower within 30 min post-CVS than post-ice pack (

conclusionsAlthough these results require interpretative caution, CVS was found to modulate pain relative to an ice pack control. CVS also modulated allodynia in some cases. CVS should be examined for pain management efficacy using randomised controlled trials.

Indexed as

allodyniacaloric vestibular stimulationcomplex regional pain syndromenon-invasive brain stimulationpersistent painphantom limb painspinal cord injury painvestibular neuromodulation

Identifiers

PMID39457677
PMCPMC11505407

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.