Evidence map›Paper›PMID 39457585›Full record

ArticleBiomedicines2024

Deferasirox's Anti-Chemoresistance and Anti-Metastatic Effect on Non-Small Cell Lung Carcinoma.

Yamixa Delgado, Anamaris Torres-Sanchez, Daraishka Perez, Grace Torres, Sthephanie Estrada, Natalia Ortiz Alvelo, Jaisy Vega, Laurie Santos, Aracelis Torres, Bismark A Madera and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Iron and the lung: emerging roles of iron metabolism in pulmonary disease pathogenesis and therapy.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yamixa DelgadoBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.ORCID 0000-0002-0686-7145
Anamaris Torres-SanchezBiology Department, University of Puerto Rico-Rio Piedras, San Juan, PR 00925, USA.ORCID 0000-0002-5726-255X
Daraishka PerezBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.
Grace TorresBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.
Sthephanie EstradaBiology Department, University of Puerto Rico-Rio Piedras, San Juan, PR 00925, USA.
Natalia Ortiz AlveloBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.
Jaisy VegaBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.
Laurie SantosBiomedical Graduate Program, Universidad Central del Caribe, Bayamón, PR 00960, USA.
Aracelis TorresBiochemistry & Pharmacology Department, San Juan Bautista School of Medicine, Caguas, PR 00725, USA.
Bismark A MaderaMolecular Sciences Research Center, University of Puerto Rico, San Juan, PR 00926, USA.ORCID 0000-0001-7925-4641
Yancy Ferrer-AcostaDepartment of Anatomy and Neurobiology, School of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA.ORCID 0000-0001-6489-3272

Funding

SCIENCE AND TECHNOLOGY COMPETENCY & EDUCATION CORE (STCE)P20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Jose R. Rodriguez-Medina · 2012 to 2026
$52.9M
The Role of Sensory Input to Mammalian Locomotion After the Loss of supraspinal.P20GM103642 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LASALDE-DOMINICCI, JOSE ANTONIO · 2013 to 2023
$20.6M
Fundación Intellectus Research FellowshipNIGMS NIH HHS P20 GM103475NIGMS NIH HHS P20GM103475NIGMS NIH HHS P20 GM103642NIGMS NIH HHS P20GM103642Sloan Scholars Mentoring Network Career Development GrantSloan Scholars Mentoring Network Seed Grant
6 · The paper itself

Abstract

Clinically approved iron chelators, originally designed to address iron overload disorders, have emerged as potential anticancer agents. Deferasirox (Def), a tridentate iron chelator, has demonstrated antiproliferative effects in cancer.

Indexed as

chemoresistancedeferasiroxiron chelatorsmetastasisnon-small cell lung carcinomaribonucleotide reductase

Identifiers

PMID39457585
PMCPMC11505511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.