Evidence map›Paper›PMID 39457522›Full record

ArticleBiomedicines2024

Bacterial and Viral Co-Infections in COVID-19 Patients: Etiology and Clinical Impact.

Ivelina Trifonova, Iveta Madzharova, Neli Korsun, Viktoria Levterova, Petar Velikov, Silvya Voleva, Ivan Ivanov, Daniel Ivanov, Ralitsa Yordanova, Tatiana Tcherveniakova and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ivelina TrifonovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-4543-6831
Iveta MadzharovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-1965-7550
Neli KorsunNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-3188-2283
Viktoria LevterovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Petar VelikovInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0000-0002-7436-4064
Silvya VolevaInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Ivan IvanovInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0000-0003-3320-5697
Daniel IvanovInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0009-0001-7360-4302
Ralitsa YordanovaInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0009-0009-8456-8851
Tatiana TcherveniakovaInfectious Disease Hospital "Prof. Ivan Kirov", Department for Infectious Diseases, Parasitology and Tropical Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Svetla AngelovaClinical Virology Laboratory, University Hospital "Prof. Dr. Stoyan Kirkovich", Trakia University, 6000 Stara Zagora, Bulgaria.
Iva ChristovaNational Laboratory "Influenza and ARD", Department of Virology, National Centre of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMixed infections can worsen disease symptoms. This study investigated the impact of mixed infections with viral and bacterial pathogens in patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

methodsUsing the in-house multiplex PCR method, we tested 337 SARS-CoV-2 positive samples for co-infections with three bacterial and 14 other viral pathogens.

resultsBetween August 2021 and May 2022, 8% of 337 SARS-CoV-2-positive patients had bacterial co-infections, 5.6% had viral co-infections, and 1.4% had triple mixed infections. The most common causes of mixed infections were

conclusionsRegular multiplex testing is important for prompt treatment and targeted antibiotic use.

Indexed as

co-infectionHaemophilus influenzaerespiratory virusesRSVSARS-CoV-2

Identifiers

PMID39457522
PMCPMC11505336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.