Evidence map›Paper›PMID 39457415›Full record

ArticleGenes2024

CRABP1 Enhances the Proliferation of the Dermal Papilla Cells of Hu Sheep through the Wnt/β-catenin Pathway.

Zahid Hussain, Tingyan Hu, Yuan Gou, Mingliang He, Xiaoyang Lv, Shanhe Wang, Wei Sun

Abstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zahid HussainCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Tingyan HuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yuan GouCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Mingliang HeCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-6157-1171
Xiaoyang LvCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Shanhe WangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0003-2888-7515
Wei SunCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.

Funding

Jiangsu 333 Distinguished Talents Project Foundation (2022) 2-323Jiangsu Agricultural Science and Technology Innovation Fund CX (23)1036the Distinguished Talents Project Foundation of Yangzhou University Nothe Natural Science Foundation of china 32172689the Natural Science Foundation of Jiangsu Province BK20210810the Natural Science Foundation of the Jiangsu Higher Education Institutions of China 22KJA230001the Project of Jiangsu Innovation Support Programme for International Science and Technology Cooperation - "Belt and Road" Innovation Cooperation BZ2023009
6 · The paper itself

Abstract

backgroundThe homologous proteins identified as cellular retinoic acid-binding proteins I and II (

methodsInitially, overexpression and inhibition of CRABP1 in the DPCs were conducted through overexpression vector and siRNA. CCK-8, EDU, and RT-PCR cell cycle assays and immunostaining were performed to evaluate the proliferation and cell cycle of dermal papilla cells (DPCs). Although, the influence of CRABP1 upon β-catenin in dermal papilla cells (DPCs) was found using immunofluorescence labeling. Finally, RT-PCR was conducted to assess the impact of CRABP1 on the expression levels of CTNNB1, TCF4, and LEF1 in DPCs involved in the Wnt/β-catenin signaling pathway.

resultsThe results showed that CRABP1 overexpression promotes the growth rates of DPCs and significantly enhances the proportion of S-phase cells compared with the control group (

conclusionsThis study found that

Indexed as

beta CateninCell ProliferationHair FollicleReceptors, Retinoic AcidWnt Signaling PathwayAnimalsCells, CulturedDermisLymphoid Enhancer-Binding Factor 1Sheepbeta CateninLymphoid Enhancer-Binding Factor 1Receptors, Retinoic Acidretinoic acid binding protein I, cellularretinoic acid binding protein II, cellularCRABP1dermal papilla cellsproliferationsheepWnt/β-catenin

Identifiers

PMID39457415
PMCPMC11507202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.