Evidence map›Paper›PMID 39457218›Full record

ArticleChildren (Basel, Switzerland)2024

Iontophoresis Improves the Impact on the Quality of Life of Children with Primary Hyperhidrosis-A Prospective Study and a Short Review.

Florentina Nastase, Camelia Busila, Alin Codrut Nicolescu, Cristina Mihaela Marin, Alin Laurentiu Tatu

Registry-linked trialAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07788326 (20% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar Hyperhydrosis), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07788326 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

20% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar Hyperhydrosis: A Controlled Randomised Study.

TypeinterventionalSponsorFayoum University HospitalRan2026 to 2027Enrolled50ConditionsHyperhidrosisArmsGroup A, Group B
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Florentina NastaseNeuropsychomotor Rehabilitation Department, "Sf. Ioan" Emergency Clinical Hospital for Children, 800487 Galati, Romania.
Camelia BusilaClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.
Alin Codrut Nicolescu"Agrippa Ionescu" Emergency Clinical Hospital, 011773 Bucharest, Romania.
Cristina Mihaela MarinClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.
Alin Laurentiu TatuClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.ORCID 0000-0003-4290-7068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary hyperhidrosis (PH) is a somatic and idiopathic pediatric skin disease. The eccrine glands are tiny and very numerous, with approximately 3 million distributed throughout the skin. There is no commonly accepted amount of sweating to define hyperhidrosis, but people with this disease suffer real limitations integrating into society, which can be quantified through quality of life measurement scales. We want to draw attention to this disease and its impact on children's quality of life because it is significant and there are no studies conducted on groups consisting solely of children.

methodsThere are various quality of life evaluation questionnaires for hyperhidrosis. We studied 103 children with hyperhidrosis by monitoring their sweat severity and its impact on quality of life, using the Hyperhidrosis Disease Severity Scale. We compared the scale results before and after 10 days of iontophoresis. This study includes only children under 18 years old, treated with iontophoresis.

resultsThe average age of the group is 11.84 ± 2.89 years. Treatment success is recorded in 68 (66.02%) children, but a change in the score is recorded in 74 (71.84%) children. The average HDSS score at T0 is 2.95 ± 0.70, compared to the HDSS score at T1 of 1.92 ± 0.86.

conclusionsHyperhidrosis has a negative impact on daily life, especially self-esteem, occupational productivity, emotional well-being, and interpersonal relationships. Iontophoresis is a safe and effective treatment method that reduces the severity of hyperhidrosis and increases the quality of life.

Indexed as

evaluationhyperhidrosisiontophoresisquality of life

Identifiers

PMID39457218
PMCPMC11506013

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