Evidence map›Paper›PMID 39457088›Full record

ReviewInternational journal of molecular sciences2024

The Trigeminal Sensory System and Orofacial Pain.

Hyung Kyu Kim, Ki-Myung Chung, Juping Xing, Hee Young Kim, Dong-Ho Youn

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. The Pathophysiological Mechanisms of Glia in Animal Models of Chronic Orofacial Pain: A Systematic Review.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  8. Article
  9. Article
  10. Aloin attenuates NMDA receptor by modulating calcium response on substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  11. Article
  12. Observational
  13. Article
  14. Pontine infarction isolated to trigeminal sensory fibers: a case report.Frontiers in pain research (Lausanne, Switzerland) · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyung Kyu KimDepartment of Physiology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Ki-Myung ChungDepartment of Physiology and Neuroscience, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.ORCID 0000-0002-1920-2521
Juping XingDepartment of Physiology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Hee Young KimDepartment of Physiology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Dong-Ho YounDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trigeminal sensory system consists of the trigeminal nerve, the trigeminal ganglion, and the trigeminal sensory nuclei (the mesencephalic nucleus, the principal nucleus, the spinal trigeminal nucleus, and several smaller nuclei). Various sensory signals carried by the trigeminal nerve from the orofacial area travel into the trigeminal sensory system, where they are processed into integrated sensory information that is relayed to higher sensory brain areas. Thus, knowledge of the trigeminal sensory system is essential for comprehending orofacial pain. This review elucidates the individual nuclei that comprise the trigeminal sensory system and their synaptic transmission. Additionally, it discusses four types of orofacial pain and their relationship to the system. Consequently, this review aims to enhance the understanding of the mechanisms underlying orofacial pain.

Indexed as

Facial PainTrigeminal NerveTrigeminal NucleiAnimalsHumansSynaptic TransmissionTrigeminal Ganglionbrainstem parasympathetic systemburning mouth syndromeheadachemesencephalic nucleusorofacial neuropathic painparatrigeminal nucleusprincipal nucleusspinal trigeminal nucleussynaptic transmissiontrigeminal gangliontrigeminal neuralgiatrigeminal sensory nuclei

Identifiers

PMID39457088
PMCPMC11508441

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.