Evidence map›Paper›PMID 39456974›Full record

ArticleInternational journal of molecular sciences2024

Whole Genome Sequencing Analysis of Model Organisms Elucidates the Association Between Environmental Factors and Human Cancer Development.

Shinya Hasegawa, Yutaka Shoji, Mamoru Kato, Asmaa Elzawahry, Momoko Nagai, Min Gi, Shugo Suzuki, Hideki Wanibuchi, Sachiyo Mimaki, Katsuya Tsuchihara and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shinya HasegawaDepartment of Environmental Health Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.ORCID 0000-0003-2731-8097
Yutaka ShojiDepartment of Food Science and Nutrition, Shizuoka Eiwa Gakuin University Junior College, 1769 Ikeda, Suruga-ku, Shizuoka 422-8545, Japan.ORCID 0000-0001-7837-3411
Mamoru KatoDivision of Bioinformatics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Asmaa ElzawahryDivision of Bioinformatics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Momoko NagaiDivision of Bioinformatics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Min GiDepartment of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.ORCID 0000-0003-1642-8127
Shugo SuzukiDepartment of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.ORCID 0000-0001-8938-9670
Hideki WanibuchiDepartment of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Sachiyo MimakiDivision of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.
Katsuya TsuchiharaDivision of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.ORCID 0000-0001-7507-2349
Yukari TotsukaDepartment of Environmental Health Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.

Funding

Japan Agency for Medical Research and Development 18ck0106264h0002, 20ck0106545h0001National Cancer Center Research and Development Fund 23-A-8, 25-A-5 and 26-A-8
6 · The paper itself

Abstract

Determining a novel etiology and mechanism of human cancer requires extraction of characteristic mutational signatures derived from chemical substances. This study explored the mutational signatures of

Indexed as

MutationSalmonella typhimuriumBile Acids and SaltsCholangiocarcinomaHumansNeoplasmsWhole Genome SequencingBile Acids and Salts1,2-dichloropropaneinducible nitric oxide synthasemutational signatureN-nitroso bile acid conjugatesoccupational cholangiocarcinoma

Identifiers

PMID39456974
PMCPMC11508241

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.