Evidence map›Paper›PMID 39456890›Full record

ArticleInternational journal of molecular sciences2024

Characterization of EpCAM-Positive and EpCAM-Negative Tumor Cells in Early-Stage Breast Cancer.

Vladimir M Perelmuter, Evgeniya S Grigoryeva, Vladimir V Alifanov, Anna Yu Kalinchuk, Elena S Andryuhova, Olga E Savelieva, Ivan A Patskan, Olga D Bragina, Evgeniy Yu Garbukov, Mariya A Vostrikova and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vladimir M PerelmuterThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Evgeniya S GrigoryevaThe Laboratory of Molecular Therapy of Cancer, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Vladimir V AlifanovThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.ORCID 0000-0002-3025-4445
Anna Yu KalinchukThe Laboratory of Molecular Therapy of Cancer, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Elena S AndryuhovaThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Olga E SavelievaThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.ORCID 0000-0002-0301-8455
Ivan A PatskanThe Laboratory of Molecular Therapy of Cancer, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Olga D BraginaThe Department of Nuclear Therapy and Diagnostics, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Evgeniy Yu GarbukovThe Department of General Oncology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Mariya A VostrikovaThe Department of General Oncology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Marina V ZavyalovaThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Evgeny V DenisovThe Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.ORCID 0000-0003-2923-9755
Nadezhda V CherdyntsevaThe Laboratory of Molecular Oncology and Immunology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.
Liubov A TashirevaThe Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634009, Russia.ORCID 0000-0003-2061-8417

Funding

Russian Science Foundation 23-15-00135
6 · The paper itself

Abstract

Most studies on CTCs have focused on isolating cells that express EpCAM. In this study, we emphasize the presence of EpCAM-negative and EpCAM

Indexed as

Biomarkers, TumorBreast NeoplasmsEpithelial Cell Adhesion MoleculeNeoplastic Cells, CirculatingAC133 AntigenCD24 AntigenCell Line, TumorEpithelial-Mesenchymal TransitionFemaleHumansMiddle AgedNeoplasm StagingNeoplastic Stem CellsAC133 AntigenBiomarkers, TumorCD24 AntigenEPCAM protein, humanEpithelial Cell Adhesion Moleculebreast cancercirculating tumor cellsmetastasis

Identifiers

PMID39456890
PMCPMC11508537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.