Evidence map›Paper›PMID 39456778›Full record

ArticleInternational journal of molecular sciences2024

Epigenetic Modifications Are Involved in Transgenerational Inheritance of Cadmium Reproductive Toxicity in Mouse Oocytes.

Jiaqiao Zhu, Shuai Guo, Jiangqin Cao, Hangbin Zhao, Yonggang Ma, Hui Zou, Huiming Ju, Zongping Liu, Junwei Li

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaqiao ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Shuai GuoCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jiangqin CaoCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Hangbin ZhaoCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Yonggang MaCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Hui ZouCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Huiming JuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Zongping LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-9071-8363
Junwei LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-5189-0299

Funding

the Natural Science Foundation of Jiangsu Province BK20221284
6 · The paper itself

Abstract

Maternal cadmium exposure during pregnancy has been demonstrated to have detrimental effects on offspring development. However, the impact of maternal cadmium exposure on offspring oocytes remains largely unknown, and the underlying mechanisms are not fully understood. In this study, we found that maternal cadmium exposure during pregnancy resulted in selective alteration in epigenetic modifications of mouse oocytes in offspring, including a decrease in H3K4me2 and H4K12ac, as well as an increase in DNA methylation of

Indexed as

CadmiumDNA MethylationEpigenesis, GeneticHistonesOocytesAnimalsDNA DamageEmbryonic DevelopmentFemaleMaleMaternal ExposureMicePregnancyPrenatal Exposure Delayed EffectsReactive Oxygen SpeciesReproductionCadmiumHistonesReactive Oxygen Speciescadmiumepigenetic modificationsoffspring oocytesoocyte maturation

Identifiers

PMID39456778
PMCPMC11507422

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.