Evidence map›Paper›PMID 39456772›Full record

ArticleInternational journal of molecular sciences2024

Metagenomic Study Reveals Phage-Bacterial Interactome Dynamics in Gut and Oral Microbiota in Pancreatic Diseases.

Laura Vilà-Quintana, Esther Fort, Laura Pardo, Maria T Albiol-Quer, Maria Rosa Ortiz, Montserrat Capdevila, Anna Feliu, Anna Bahí, Marc Llirós, Adelaida García-Velasco and 9 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Laura Vilà-QuintanaDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.ORCID 0000-0001-7495-0031
Esther FortDepartment of Gastroenterology, Hospital Universitari de Girona Dr. Josep Trueta, 17007 Girona, Spain.
Laura PardoDepartment of Gastroenterology, Hospital Universitari de Girona Dr. Josep Trueta, 17007 Girona, Spain.
Maria T Albiol-QuerHepato-Pancreato-Biliary Unit, Department of Surgery, Hospital Universitari de Girona Dr. Josep Trueta, 17007 Girona, Spain.
Maria Rosa OrtizDepartment of Pathology, Hospital Universitari de Girona Dr. Josep Trueta, 17007 Girona, Spain.ORCID 0000-0002-8973-0493
Montserrat CapdevilaDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.ORCID 0000-0003-0649-9773
Anna FeliuDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.
Anna BahíDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.ORCID 0000-0001-9774-9218
Marc LlirósBioinformatics and Bioimaging (BI-SQUARED) Research Group, Biosciences Department, Faculty of Sciences, Technology and Engineering, Universitat de Vic, 08500 Vic, Spain.ORCID 0000-0001-8456-4230
Adelaida García-VelascoPrecision Oncology Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.ORCID 0000-0001-8388-0522
Mireia Morell GinestàHereditary Cancer Program, Institut Català d'Oncologia (ICO), Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), CIBERONC, 08908 Barcelona, Spain.ORCID 0000-0002-1708-0110
Berta LaquenteMedical Oncology Department, Institut Català d'Oncologia (ICO), Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), 08908 Barcelona, Spain.
Débora PozasDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.
Victor MorenoInstitut Català d'Oncologia (ICO), Institut de Recerca Biomedica de Bellvitge (IDIBELL), 08908 Barcelona, Spain.ORCID 0000-0002-2818-5487
Librado Jesús Garcia-GilDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.
Eric Jeffrey DuellCancer Epidemiology Research Program, Unit of Nutrition and Cancer, Institut Català d'Oncologia (ICO), Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), 08908 Barcelona, Spain.
Ville Nikolai PimenoffDepartment of Clinical Science, Intervention and Technology-CLINTEC, Karolinska Institutet, 14152 Stockholm, Sweden.
Robert Carreras-TorresDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.ORCID 0000-0002-2925-734X
Xavier AldeguerDigestive Diseases and Microbiota Group, Girona Biomedical Research Institute (IDIBGI), 17190 Salt, Spain.

Funding

European Molecular Biology Organization 9986Fundació la Marató de TV3 201912-31
6 · The paper itself

Abstract

Individuals with pancreatic-related health conditions usually show lower diversity and different composition of bacterial and viral species between the gut and oral microbiomes compared to healthy individuals. We performed a thorough microbiome analysis, using deep shotgun sequencing of stool and saliva samples obtained from patients with chronic pancreatitis (CP), pancreatic ductal adenocarcinoma (PDAC), and healthy controls (HCs).We observed similar microbiota composition at the species level in both the gut and oral samples in PDAC patients compared to HCs, among which the most distinctive finding was that the abundance of oral-originated

Indexed as

BacteriophagesFecesGastrointestinal MicrobiomeMetagenomicsAdultAgedBacteriaCarcinoma, Pancreatic DuctalFemaleHumansMaleMetagenomeMicrobiotaMiddle AgedMouthPancreatic Diseasesbacteriachronic pancreatitisgut microbiomemetagenome analysisoral microbiomepancreatic cancerpancreatic diseasesphage–bacterial interactomevirus

Identifiers

PMID39456772
PMCPMC11507633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.