Evidence map›Paper›PMID 39456644›Full record

ArticleCancers2024

Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection.

Katsuji Sawai, Takanori Goi, Youhei Kimura, Kenji Koneri

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katsuji SawaiFirst Department of Surgery, University of Fukui, Fukui 910-1193, Japan.
Takanori GoiFirst Department of Surgery, University of Fukui, Fukui 910-1193, Japan.ORCID 0000-0001-7671-0648
Youhei KimuraFirst Department of Surgery, University of Fukui, Fukui 910-1193, Japan.
Kenji KoneriFirst Department of Surgery, University of Fukui, Fukui 910-1193, Japan.ORCID 0000-0003-1344-149X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer is a major global health burden, with surgical resection being the standard treatment aimed at curative tumor removal. Oxidative stress plays a crucial role in colorectal cancer progression and prognosis. This study hypothesized that physical removal of colorectal cancer, a primary source of oxidative stress, would reduce blood levels of reactive oxygen metabolite derivatives (d-ROMs), a marker of oxidative stress, and biologic antioxidant potential (BAP) levels, a marker of antioxidant potential.

methodsThis study included 123 patients who underwent radical resection for colorectal cancer. d-ROM and BAP levels were measured before and one month after surgery.

resultsThe clinicopathological analysis showed a correlation between preoperative d-ROM levels and tumor size (

conclusionsThese results suggest that d-ROMs could serve as a valuable biomarker for monitoring tumor burden and surgical efficacy in patients with colorectal cancer.

Indexed as

biologic antioxidant potentialcolorectal cancer resectionoxidative stressreactive oxygen metabolite derivatives

Identifiers

PMID39456644
PMCPMC11505646

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.