Evidence map›Paper›PMID 39456429›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Effect of Curcumin Intake on Skeletal Muscle Oxygen Saturation Parameters in Older Participants.

Olavo João Frederico Ramos-Junior, Vivian Dos Santos Pinheiro, Tatiane Gomes Dos Santos de Souza, Thiago Silveira Alvares

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olavo João Frederico Ramos-JuniorNutrition and Exercise Metabolism Research Group, Federal University of Rio de Janeiro, Macaé 27971-525, RJ, Brazil.ORCID 0000-0002-7670-9927
Vivian Dos Santos PinheiroNutrition and Exercise Metabolism Research Group, Federal University of Rio de Janeiro, Macaé 27971-525, RJ, Brazil.ORCID 0000-0002-7787-9944
Tatiane Gomes Dos Santos de SouzaNutrition and Exercise Metabolism Research Group, Federal University of Rio de Janeiro, Macaé 27971-525, RJ, Brazil.
Thiago Silveira AlvaresNutrition and Exercise Metabolism Research Group, Federal University of Rio de Janeiro, Macaé 27971-525, RJ, Brazil.ORCID 0000-0002-2261-8501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAging is associated with increased reactive oxygen species (ROS) and reduced bioavailability of nitric oxide (NO). Curcumin has been shown to increase NO bioavailability due to its ability to neutralize ROS, preventing oxidative stress. The present study aimed to investigate the effect of curcumin intake on skeletal muscle oxygen parameters and exercise tolerance in response to exercise in older people. Changes in circulating levels of NO metabolites were also investigated.

methodsOlder subjects consumed 10 g of turmeric root extract from

resultsDuring exercise, the amplitude of deoxyhemoglobin was greater after curcumin intake compared to placebo (CUR: 13.11 ± 9.52 vs. PLA: 10.22 ± 8.39 μM,

conclusionsThe present study suggests that curcumin improves muscle oxygenation status at the capillary level in older adults by possibly improving muscle oxygen extraction and/or delivery, with no effect on exercise tolerance.

Indexed as

agingbioactive compoundscurcuminmuscle oxygen saturationnitric oxide

Identifiers

PMID39456429
PMCPMC11505174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.