Evidence map›Paper›PMID 39456415›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Protective Effects of Anethole in

Jeong Won Seo, Sarmin Ummey Habiba, Yeasmin Akter Munni, Ho Jin Choi, Asma Aktar, Kishor Mazumder, Deuk-Young Nah, In-Jun Yang, Il Soo Moon

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. The Role of the Gut Microbiota in Vascular Physiology and Health.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Multivalent Neuroprotective Activity ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Neurotrophic Effects ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeong Won SeoDivision of Cardiology, Department of Internal Medicine, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Sarmin Ummey HabibaDepartment of Anatomy, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0003-3213-0179
Yeasmin Akter MunniDepartment of Anatomy, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0001-5232-7214
Ho Jin ChoiDepartment of Anatomy, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.
Asma AktarDepartment of Pharmacy, Jashore University of Science and Technology, Jashore 7408, Bangladesh.
Kishor MazumderDepartment of Pharmacy, Jashore University of Science and Technology, Jashore 7408, Bangladesh.ORCID 0000-0002-8711-7409
Deuk-Young NahDivision of Cardiology, Department of Internal Medicine, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0002-3943-9075
In-Jun YangDepartment of Physiology, College of Korean Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0002-6113-1325
Il Soo MoonDepartment of Anatomy, College of Medicine, Dongguk University, Gyeongju 38066, Republic of Korea.ORCID 0000-0002-1608-016X

Funding

Korean Health Technology R&D Project HF22C0005National Research Foundation of Korea (NRF) (NRF-2021R1A2C1008564National Research Foundation of Korea (NRF) NRF-2021R1I1A2048979National Research Foundation of Korea (NRF) NRF-2022R1A6A3A01087627
6 · The paper itself

Abstract

backgroundActive compounds from plants and herbs are increasingly incorporated into modern medical systems to address cardiovascular diseases (CVDs).

methodsProtective effects against cellular damage were assessed in the H9C2 cardiomyocyte hypoxia/reoxygenation (H/R) experimental model. The identities of phytochemicals in FVSE were determined by GC-MS analysis. The phytochemical's potential for nutrients and pharmacokinetic properties was assessed by ADMET analysis.

resultsGC-MS analysis of the ethanol extracts of

conclusionsThese findings highlight the therapeutic potential of FVSE and its prominent component, anethole, in the treatment of CVDs, particularly those associated with hypoxia-induced damage.

Indexed as

ADMETboiled-egg modelDNA double-strand break damageFoeniculum vulgare Mill.GC-MSH9C2mitochondrial membrane potentialnuclear condensationROS

Identifiers

PMID39456415
PMCPMC11504384

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.