Evidence map›Paper›PMID 39456158›Full record

ArticleBiomolecules2024

Chloramphenicol Interferes with 50S Ribosomal Subunit Maturation via Direct and Indirect Mechanisms.

Ting Yu, Fuxing Zeng

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Sublethal Concentration of Chloramphenicol Threatens the Health ofInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ting YuDepartment of Systems Biology, School of Life Sciences, Southern University of Science and Technology, No. 1088 Xueyuan Avenue, Shenzhen 518055, China.
Fuxing ZengDepartment of Systems Biology, School of Life Sciences, Southern University of Science and Technology, No. 1088 Xueyuan Avenue, Shenzhen 518055, China.ORCID 0000-0003-0790-0151

Funding

Guangdong Innovative and Entrepreneurial Research Team Program 2021ZT09Y104Guangdong Program 2021QN02Y353National Natural Science Foundation of China 32171200National Natural Science Foundation of China 92169111Shenzhen Science and Technology Program JCYJ20220530115210023
6 · The paper itself

Abstract

Chloramphenicol (CAM), a well-known broad-spectrum antibiotic, inhibits peptide bond formation in bacterial ribosomes. It has been reported to affect ribosome assembly mainly through disrupting the balance of ribosomal proteins. The present study investigates the multifaceted effects of CAM on the maturation of the 50S ribosomal subunit in

Indexed as

ChloramphenicolCryoelectron MicroscopyEscherichia coliRibosomal ProteinsAnti-Bacterial AgentsEscherichia coli ProteinsRibosome Subunits, Large, BacterialAnti-Bacterial AgentsChloramphenicolEscherichia coli ProteinsRibosomal Proteins50S precursorchloramphenicolcryo-EMribosome biogenesis

Identifiers

PMID39456158
PMCPMC11505724

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.