Evidence map›Paper›PMID 39456153›Full record

ArticleBiomolecules2024

PMSFF: Improved Protein Binding Residues Prediction through Multi-Scale Sequence-Based Feature Fusion Strategy.

Yuguang Li, Xiaofei Nan, Shoutao Zhang, Qinglei Zhou, Shuai Lu, Zhen Tian

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuguang LiSchool of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou 450001, China.
Xiaofei NanSchool of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-9145-1111
Shoutao ZhangSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Qinglei ZhouSchool of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou 450001, China.
Shuai LuSchool of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-9489-0611
Zhen TianSchool of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0003-0945-8168

Funding

General Project of National Natural Science Foundation of China 61572444Key Research and Development Projects in Henan Province 241111210500Major Science and Technology Projects in Henan Province 201400210400National Natural Science Foundation of China 62371423
6 · The paper itself

Abstract

Proteins perform different biological functions through binding with various molecules which are mediated by a few key residues and accurate prediction of such protein binding residues (PBRs) is crucial for understanding cellular processes and for designing new drugs. Many computational prediction approaches have been proposed to identify PBRs with sequence-based features. However, these approaches face two main challenges: (1) these methods only concatenate residue feature vectors with a simple sliding window strategy, and (2) it is challenging to find a uniform sliding window size suitable for learning embeddings across different types of PBRs. In this study, we propose one novel framework that could apply multiple types of PBRs

Indexed as

Protein BindingProteinsAlgorithmsAmino Acid SequenceBinding SitesComputational BiologyDatabases, ProteinSequence Analysis, ProteinProteinsattention mechanismdeep learningprotein binding residuessequence-based feature

Identifiers

PMID39456153
PMCPMC11506650

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.