Evidence map›Paper›PMID 39456015›Full record

ArticleBMC psychiatry2024

The role of gender factors influencing multiple dimensions of somatic symptoms in major depressive disorder patients with suicidal ideation: insights from the Chinese NSSD study.

Ruizhi Mao, Jingjing Xu, Daihui Peng, Jun Chen, Zhiguo Wu, Yiru Fang

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Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ruizhi MaoClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jingjing XuShanghai Huangpu District Mental Health Center, Shanghai, China.
Daihui PengClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jun ChenClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhiguo WuDepartment of Psychological Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. zhiguo_wu@yeah.net.
Yiru FangClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yirufang@aliyun.com.

Funding

Key Supporting Projects of Clinical Research Center of Shanghai Mental Health Center SHDC2020CR6023National Natural Science Foundation of China 82401783National Natural Science Foundation of China 91232719Shanghai Key Project of Science and Technology 2018SHZDZX05Shanghai University of Medicine & Health Sciences Foundation 20MC2020005Shanghai Yangpu District Health Commission Foundation 22YPZB10the Capability Promotion Project for Research-oriented Doctor at SMHC 2021-YJXYS-03
6 · The paper itself

Abstract

backgroundThe study aimed to explore the influence of gender on the prevalence of various somatic symptoms and their associations with suicidal ideation (SI) among patients with major depressive disorder (MDD).

methodsWe recruited 3,275 patients with MDD from the National Survey on Symptomatology of Depression (NSSD), among whom 1,745 patients had SI. The clinical characteristics and the prevalence of somatic symptoms across 20 dimensions in MDD patients with SI were compared between male and female patients. Spearman correlation analysis and logistic regression analysis were used to explore the relationship between somatic symptoms and SI.

resultsIn patients with SI, 32.2% of female participants attributed the onset of MDD to physical concerns, whereas 27% of male patients held a similar perspective (P = 0.032). Female patients exhibited a higher prevalence of early insomnia (64.6% vs. 70.2%) and a lower prevalence of hypersomnia (17.2% vs. 12.9%) and urinary system symptoms (25.0% vs. 17.8%). Logistic regression analysis indicated that female patients displayed a broader range of somatic symptoms identified as risk factors for SI, including increased appetite, respiratory symptoms, circulatory system symptoms, limb pain, and various others.

conclusionThis study unveils gender-specific patterns in somatic symptoms among MDD patients with SI, highlighting the clinical significance of these symptoms in diagnosis and intervention. Understanding how physical concerns contribute to MDD, especially among females, underscores the need for tailored clinical approaches. Recognizing and addressing these symptoms could guide more effective suicide prevention strategies and enhance MDD management in clinical practice.

Indexed as

Major Depressive DisorderSuicidal IdeationAdultChinaEast Asian PeopleFemaleHumansMaleMedically Unexplained SymptomsMiddle AgedPrevalenceRisk FactorsSex FactorsSleep Initiation and Maintenance DisordersYoung AdultGender factorsMajor depressive disorderSomatic symptomSuicidal ideation

Identifiers

PMID39456015
PMCPMC11515138

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