Evidence map›Paper›PMID 39455823›Full record

ArticleNPJ digital medicine2024

Transmission line model as a digital twin for abdominal aortic aneurysm patients.

Donghyeon Kim, Divyesh Narayanan, Shih-Hsien Sung, Hao-Min Cheng, Chen-Huan Chen, Chang-Sei Kim, Ramakrishna Mukkamala, Jin-Oh Hahn

Abstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Feel the force: Biomechanical homeostasis of the cardiovascular system.Journal of translational internal medicine · 2026
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donghyeon KimMechanical Engineering, University of Maryland, College Park, MD, 20742, USA.ORCID http://orcid.org/0000-0002-1195-8666
Divyesh NarayananBioengineering, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Shih-Hsien SungMedicine, National Yang Ming University, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-9441-1836
Hao-Min ChengMedicine, National Yang Ming University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-3885-6600
Chen-Huan ChenMedicine, National Yang Ming University, Taipei, Taiwan.
Chang-Sei KimMechanical Engineering, Chonnam National University, Gwangju, Korea.ORCID http://orcid.org/0000-0003-4532-2006
Ramakrishna MukkamalaBioengineering, University of Pittsburgh, Pittsburgh, PA, 15261, USA. rmukkamala@pitt.edu.ORCID http://orcid.org/0000-0001-8918-4050
Jin-Oh HahnMechanical Engineering, University of Maryland, College Park, MD, 20742, USA. jhahn12@umd.edu.ORCID http://orcid.org/0000-0001-5429-2836

Funding

Towards a Convenient, Point-of-Care Device for Screening and Surveillance of Aortic AneurysmsR21EB029376 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MUKKAMALA, RAMAKRISHNA · 2021 to 2021
$410k
NIBIB NIH HHS R21 EB029376U.S. Department of Health & Human Services | National Institutes of Health (NIH) 1R21EB029376
6 · The paper itself

Abstract

We investigated the potential of the transmission line model as a digital twin of aneurysmal aorta by comparatively analyzing how a uniform lossless tube-load model were fitted to the carotid and femoral artery tonometry waveforms pertaining to (i) 79 abdominal aortic aneurysm (AAA) patients vs their matched controls (CON) and (ii) 35 AAA patients before vs after endovascular aneurysm repair (EVAR). The uniform lossless tube-load model fitted the tonometry waveforms pertaining to AAA as well as CON and EVAR. In addition, the parameters in the tube-load model exhibited physiologically explainable changes: when normalized, both pulse transit time and reflection coefficient increased with AAA and decreased after EVAR, which can be explained by the increase in arterial compliance and the decrease in arterial inertance due to the aortic expansion associated with AAA. In sum, the tube-load model may have the potential as a digital twin to enable personalized AAA monitoring.

Identifiers

PMID39455823
PMCPMC11511889

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.