ArticleNPJ microgravity2024
Development and implementation of a simulated microgravity setup for edible cyanobacteria.
Article in NPJ microgravity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Mechatronics Design of a Clinostat Agriculture Space System for Biomimetic Phyto-Growth in Microgravity (Phyto-G) and 3D-Motion Computer Simulation on Hydroponic Environment.Biomimetics (Basel, Switzerland) · 2026Article
- Primary Stress Factors and Adaptive Mechanisms of Microalgae in Space Environments and Their Applications in Space Life Support Systems.Plants (Basel, Switzerland) · 2026Review
- Illumination optimization and low-power trapping of Limnospira indica PCC 8005 using bulk acoustic waves in microgravity.NPJ microgravity · 2026Article
- Anabaena-a promising chassis for space exploration.NPJ microgravity · 2026Review
- Emerging Chemical and Biological Materials Technologies in the Extraplanetary Environment.Nano-micro letters · 2026Review
- Integrating resource utilization and bioregenerative life support systems for sustainable space exploration.Frontiers in microbiology · 2026Review
- Harnessing desiccation-tolerant cyanobacteria as biosensors for LexA-mediated responses in deep space.Frontiers in microbiology · 2026Article
- Exploring the role of CRISPR in advancing space biotechnology: challenges and solutions for human survival beyond earth.Frontiers in bioengineering and biotechnology · 2026Review
- Meta-analysis of extremotolerant microbes to address nutrient deficiencies in bioregenerative life support systems during Deep-space Missions.NPJ science of food · 2025Article
- Superfood potential of Chlorella vulgaris: productivity and antioxidant boost under simulated moon and microgravity conditions.NPJ microgravity · 2025Article
- The influence of different storage conditions oniScience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Regenerative life support systems for space crews recycle waste into water, food, and oxygen using different organisms. The European Space Agency's MELiSSA program uses the cyanobacterium Limnospira indica PCC8005 for air revitalization and food production. Before space use, components' compatibility with reduced gravity was tested. This study introduced a ground analog for microgravity experiments with oxygenic cyanobacteria under continuous illumination, using a random positioning machine (RPM) setup. L. indica PCC8005 grew slower under low-shear simulated microgravity, with proteome analysis revealing downregulation of ribosomal proteins, glutamine synthase, and nitrate uptake transporters, and upregulation of gas vesicle, photosystem I and II, and carboxysome proteins. Results suggested inhibition due to high oxygen partial pressure, causing carbon limitation when cultivated in low-shear simulated microgravity. A thicker stagnant fluid boundary layer reducing oxygen release in simulated microgravity was observed. These findings validate this RPM setup for testing the effects of non-terrestrial gravity on photosynthetic microorganisms.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.