Evidence map›Paper›PMID 39455579›Full record

ArticleNature communications2024

The expression of integron arrays is shaped by the translation rate of cassettes.

André Carvalho, Alberto Hipólito, Filipa Trigo da Roza, Lucía García-Pastor, Ester Vergara, Aranzazu Buendía, Teresa García-Seco, José Antonio Escudero

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

André CarvalhoMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain. apaulino@ucm.es.ORCID 0000-0002-0098-5140
Alberto HipólitoMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain.ORCID 0000-0002-6461-2650
Filipa Trigo da RozaMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain.
Lucía García-PastorMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain.
Ester VergaraMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain.
Aranzazu BuendíaVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
Teresa García-SecoVISAVET Health Surveillance Centre, Universidad Complutense de Madrid, Madrid, Spain.
José Antonio EscuderoMolecular Basis of Adaptation. Departamento de Sanidad Animal. Universidad Complutense de Madrid, Madrid, Spain. jaescudero@ucm.es.ORCID 0000-0001-8552-2956

Funding

Universidad Complutense de Madrid (Complutense University of Madrid) PhD program
6 · The paper itself

Abstract

Integrons are key elements in the rise and spread of multidrug resistance in Gram-negative bacteria. These genetic platforms capture cassettes containing promoterless genes and stockpile them in arrays of variable length. In the current integron model, expression of cassettes is granted by the P

Indexed as

Gene Expression Regulation, BacterialIntegronsPromoter Regions, GeneticProtein BiosynthesisAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialEscherichia coliRNA, MessengerAnti-Bacterial AgentsRNA, Messenger

Identifiers

PMID39455579
PMCPMC11511950

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.