Evidence map›Paper›PMID 39454226›Full record

ArticleGynecologic oncology2024

Trends in brachytherapy in utilization for vaginal cancer in the United States from 2004 to 2021.

Darien Colson-Fearon, Akila N Viswanathan

Abstract read
In one paragraph

Article in Gynecologic oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trends in brachytherapy utilization in Canada from 2011 to 2020.Physics and imaging in radiation oncology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Darien Colson-FearonDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Akila N ViswanathanDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: anv@jhu.edu.

Funding

Multiparametric Magnetic Resonance Imaging as a Novel Approach to Brachytherapy for Cervical CancerR01CA237005 · NCI · JOHNS HOPKINS UNIVERSITY · PI VISWANATHAN, AKILA · 2020 to 2024
$2.8M
NCI NIH HHS R01 CA237005
6 · The paper itself

Abstract

purposeBrachytherapy (BT) is recommended for vaginal cancer treatment, particularly cases of bulky and/or recurrent disease. However, previous studies noted a decline in utilization rates. This study examines recent trends in BT utilization to assess for reversal in trends. MATERIAL AND

methodsThis study analyzed the National Cancer Database (NCDB) of patients with FIGO stage I to IVA vaginal cancer treated between 2004 and 2021. A log binomial regression with robust variance was used to estimate incidence rate ratios (IRRs) of BT utilization over time and identify potential factors associated with receipt.

resultsBrachytherapy use increased from 48.0 % in 2004 to 63.3 % in 2021. Factors associated with increased brachytherapy use included, receiving care at an academic/research program (IRR: 1.35 95 % CI: 1.18-1.55), integrated cancer program (1.22 [1.06-1.41]), and diagnosis after 2018 (1.31 [1.21-1.42]). Factors associated with decreased use included American Indian or Alaskan Native race (0.55 [0.31-0.97]) when compared to white race, age over 70 (≥ 70-79 years: 0.91 [0.83-0.99]; ≥ 80 years: 0.68 [0.61-0.76]) when compared to age less than 50, and stage II (0.91 [0.86-0.96]), III (0.71 [0.67-0.75]), or IVA (0.43 [0.37-0.50]) disease when compared to stage I. Finally, geographic differences were also observed in BT use.

conclusionsIn patients with stage I - IVA vaginal cancer from 2004 to 2021, brachytherapy utilization has significantly increased. These results indicate a recent start of the reversal of previously identified declining use of brachytherapy. However, more work is needed to ensure equitable use across demographic strata.

Indexed as

BrachytherapyVaginal NeoplasmsAdultAgedAged, 80 and overDatabases, FactualFemaleHumansMiddle AgedNeoplasm StagingUnited StatesBrachytherapySurvivalVaginal cancer

Identifiers

PMID39454226
PMCPMC11637889

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.