Evidence map›Paper›PMID 39454122›Full record

ArticleNeurology2024

National and Subnational Trends of Mortality and Years of Life Lost Due to Stroke and Its Subtypes in Young Adults in China, 2005-2020.

Zixin Wang, Yi Ren, Wei Liu, Jiamin Li, Jiameng Li, Chen Zhang, Lijun Wang, Maigeng Zhou, Junwei Hao, Peng Yin and 1 more

Abstract read
In one paragraph

Article in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. The burden of ischemic stroke and its attributable risk factors among people aged 15-49 years in Asia, 1990-2021: results from the global burden of disease study 2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Zixin WangFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.
Yi RenFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.
Wei LiuFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.
Jiamin LiFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.
Jiameng LiFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.
Chen ZhangFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-9353-337X
Lijun WangFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-0469-0809
Maigeng ZhouFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-1046-6803
Junwei HaoFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-3075-5434
Peng YinFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-5515-2824
Qingfeng MaFrom the Department of Neurology (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Xuanwu Hospital, Capital Medical University, Beijing; National Center for Neurological Disorders (Z.W., Y.R., Jiamin Li, Jiameng Li, C.Z., J.H., Q.M.), Beijing; Zhejiang Provincial Center for Disease Control and Prevention (W.L.), Hangzhou; National Center for Chronic and Non-communicable Disease Control and Prevention (L.W., M.Z., P.Y.), Chinese Center for Disease Control and Prevention, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe incidence of stroke among young adults was rising globally, but the death burden of stroke in young adults in China is lacking. We aimed to examine the temporal trends in mortality and years of life lost (YLLs) caused by stroke among young adults from 2005 to 2020 across China.

methodsBased on the data from the National Mortality Surveillance System in China, we estimated the number and age-standardized rate of mortality and YLLs due to stroke and its subtypes among young adults aged 15-49 years during 2005-2020, for both China and its 31 mainland provinces.

resultsDuring 2005-2020, the age-standardized mortality rate of stroke among young adults aged 15-49 years in China decreased by 21.0%, from 5.9/100,000 to 4.7/100,000, and the YLL rate decreased from 286.9/100,000 to 229.5/100,000. The age-standardized mortality rate among young adults due to intracerebral hemorrhage (ICH) showed a significant downward trend with a decrease of 26.3% while that of ischemic stroke (IS) and subarachnoid hemorrhage (SAH) decreased by 4.5% and 0.6%, respectively. In 2020, the mortality rate of ICH was 3.5 times higher than that of IS (3.3/100,000 vs 0.9/100,000) among young adults in China. The male/female ratio of age-standardized mortality rate of stroke in young adults increased from 2.0 in 2005 to 3.1 in 2020. The age-standardized mortality rate of IS and SAH in young men increased by 11.0% and 2.5%, respectively. In 2020, Tibet (18.4/100,000), Jilin (10.4/100,000), and Qinghai (8.3/100,000) were the top 3 provinces holding the highest age-standardized mortality rate due to stroke among young adults. Tibet was found to have the highest mortality rate due to ICH and SAH while that of IS was higher in northeast China. DISCUSSION: In China, the death burden caused by ICH among young adults was substantially higher than that of IS. The increasing death burden of IS and SAH among young men requires special attention. Evidence-based intervention strategies are needed to improve the outcomes of stroke and alleviate the death burden due to stroke among young adults in Chinese population.

Indexed as

StrokeAdolescentAdultChinaFemaleHumansLife ExpectancyMaleMiddle AgedMortalitySubarachnoid HemorrhageYoung Adult

Identifiers

PMID39454122
PMCPMC11515115

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